Hi B.L.
I took a look around at vitex. As you know I don't profess to be a expert. But what I found on vitex leads me to believe this. For a genetic female suffering from hormone related problems. Vitex would be Ok. For a genetic male trying to feminize, no I wouldn't take it. From what I found (some of it went over my head). Vitex regulates and normalizes progesterone and prolatin. Not some thing you would want to do when trying to raise female hormones in the male body. Body builders take it to keep from having breast development due to the high levels of testoterone in their bodies. Test can aromitize into estrogen if the levels are too high.