[AbiDrew85]

The female reproductive cycle is very complex, but for my purposes I am going to concentrate only on estradiol and progesterone for the following analysis.

Estrogen starts to rise on the 3rd day of the cycle, day one being the beginning of menstruation. It peaks around the 14th day, and then sharply declines until it starts rising again on the 17th day. By day 20 estradiol has mostly stabilized at half the peak value until day 25 when it starts to fall in preparation for the next menstruation.

Progesterone starts to rise around day 14 and continues to do so until it peaks around day 22, and then starts to fall in preparation for the next menstruation.

If I were to try to approximate this in my plan, I should be using an absolute minimum dose of estrogens during days 27 to 3, double that dose from days 3 to 8, and then keep doubling my dose every two days until day 14, at which point I'd be quartering it on both the 15th and 16th days. I'd then double it on day 17, then again on day 18, then leave it steady until day 24. Then half it daily until day 27 when we return to minimum. This would be thus: 1 drop of PM from days 27 to 3, 2 drops 3 to 8, 4 - 9 & 10, 8 - 11 & 12, and 16 on 13 and 14. Then I would fourth it on day 15 back to 8, fourth again on day 16 to 2, and then double it on day 17 to 4, then 8 on day 18, and leave it steady until day 24... half it on day 25 to 4, half it on day 26 to 2, half it on day 27 to 1.

Progesterone is much much easier. Since it tends to stay in the body longer than estrogens, it is possible to simply begin dosing at an appropriate amount on day 14 and continue until day 22. Alternatively, I could dose at an 1/8th teaspoon on days 14 & 15, 1/4th tsp on days 16 & 17, 1/2 tsp 18-23, 1/4th tsp days 24 & 25, and 1/8th tsp on 26 and 27. Personally, since I'd be being so exacting with the estrogens, I may as well be with the progesterone. So I'll go with the latter method.

To throw in a bit of a monkey wrench, I'm also strongly considering buying estradiol valerate tablets from a place that is known to be of good quality and VERY CHEAP, but their cc processor is scammy... I'd buy pre-paid cards with JUST enough money on them for my order, then throw them away. I can get these tablets in packs of 56 1mg OR 2mg tablets, maximum suggested dosing is 8mg in a day.

Because of this, I would NOT TAKE IT on my "minimum" days.

So... From day 27 to day 2, NO ESTRADIOL. From day 3 through day 8, 1mg, 2mg on day 9 & 10, 4mg on 11 & 12, 8mg on 13 & 14, 3mg on day 15, 1mg on day 16, 2mg on day 17, and 4mg from days 18 to 24, 2mg on day 25, 1mg on day 26, and back to NONE on day 27.

I have attached a nice little graph of this dosing schedule:



Compare to:


Please note that I actually truncated the progesterone segment by a significant margin. This was simply to avoid having it visually dwarf the other two. I truncated it in order to line up reasonably to the PM dosing. It's actual levels are from 0 to 10 to 20 to 40 and back down. With the COMBINED estrogens, they would actually line up really really well were I to include the estrogens together as just one and leave progesterone at its actual levels. It'd look basically the same as PM to PC on the current chart.

When I say very cheap, following this dosing schedule, I'd be able to get half a years supply of the estradiol valerate for 55 USD not counting shipping and other charges.