Thanks LL, ha!, my C.O. was a complete nut job!.....I don't think he ever slept!
I've recently have been looking into the shaping of breasts, or Morphogenesis of Mammary glands (shaping of the breasts). Activation of ER-α causes elongation or horizontal growth of mammary duct cells.
Progesterone receptor activation causes side-branching of mammary gland cells.
Density, areolar gland development, and gland lactation development are caused by prolactin receptor activation.
From the table the effects of 8-prenylnaringenin on estrogen receptors are shown. 8-prenylnaringenin directly stimulates ER-α and the progesterone receptor in the mammary glands. It also indirectly stimulates the prolactin receptor by causing an increase in prolactin. 8-prenylnaringenin (hops) stimulates the hormone receptors responsible for breast growth possibly in elongation, area, areola and density.
I love what hops can do but its not easy to supplement with, at least for me!, imo.
Mammary gland development requires both systemic hormones and local growth factor-mediated tissue interactions. Classical hormone ablation/replacement experiments, and more-recent genetic analyses in mice, have shown that post-pubertal gland development requires systemic hormones from ovary [estrogen (E) and progesterone (P)], pituitary [growth hormone (GH) and prolactin (PRL)] and adrenal gland (glucocorticoids) (Topper and Freeman, 1980). Loss of ovarian or pituitary function leads to failure of hormone-dependent ductal elongation after puberty, with E and GH participating primarily in ductal elongation and P and PRL participating primarily in alveolar development. Glucocorticoids enhance (but are not essential for) ductal elongation and are required for alveolar function in lactation.
So my question was how does the breast take shape?, and this is what I found, fascinating!