[Candace]

My observation is, I don't see how anybody is immune to xenoestrogens these days given the are a part of everything we do, eat, breath etc. I bring my shopping home and 90% of it is packaged in plastic and the meats are packaged by the cheap SMELLY glad wrap that makes you sinus's want to shrivel up an die
All my supplements liquid or otherwise, all supplied in plastic bla bla you get my drift. Milk, juice, everything IN PLASTIC.

So if you want to focus on trying to eliminate Xenoestrogens by way of Dim or cruciferous veggies etc are there any other supporting nutrients you might need to take to support the body assuming you did in fact start some "die off" effect of eliminating the Xenos? I heard potentially if you don't have certain nutrients while trying to eliminate the bad estros the effects can be disasterous. IF you have covered this I apologize in advance as I haven't scrutinized the post, just the xenos caught my eye..

Second yes you need to have a good functional 'elimination process going on DOWNSTAIRS' (to put it nicely) so increase fibre by way of pysillium husks or the likes. What I want to know is can you're body get used the increased fibre like Metamucil, pysillium if you take it daily and render it ineffective or is it suitable for daily continuous use???

One strategy is to look for containers made of either glass or plastics with recycle codes 2, 4, or 5 and to never heat even those "safer" plastics. Cash register receipts have BPA so don't touch them more than necessary. Eat canned food only if you know for certain that the can lining is BPA-free.

Phase II detoxification conjugates toxins with methyl groups, acetyl groups, glutathione, sulfate, glycine, or glucuronic acid. Methylation needs folic acid (from either lemon peel extract or 5-methylfolate: the synthetic folic acid isn't completely converted in the first pass so you get unmetabolized folic acid that can mess with natural killer cells), B12, and choline. The choline RDA is tough to get: I need to supplement 7.2 g of the triple-strength lecithin. (Choline bitartrate is too poorly absorbed to bother with. I would use alpha-GPC if it was cheaper. CDP-choline is probably a bad idea because it converts to uridine which could cause a nucleic acid imbalance. Orotate converting to uridine and causing such an imbalance is thought to be the mechanism by which it increases cancer risk.) My dietary software, CRONometer, doesn't list choline so I had to add it up from this USDA database to calculate the deficiency.

Glutathione can be increased with whey protein (although whey is probably pro-aging because it's an mTOR stimulant) or something that activates Nrf2/ARE like resveratrol. The maximum benefit is at a concentration of 1 micromolar, which is close to my best guess (2 micromolar) of what you get from Revgenetics Nitro250. (Resveratrol is a supplement which needs sophisticated formulation to get absorbed. Most mainstream brands use unformulated 50% extracts, and a lot of the other 50% is emodin which is an MAO inhibitor and which also causes diarrhea at doses needed to activate Nrf2/ARE.)

I'm not sure if we need to boost sulfate. Hopefully MSM covers this base. Glycine can be obtained from gelatin, collagen, or pure glycine powder, which is sweet as sugar. Also note that glycine is able to detox methionine and extend maximum lifespan in rats. I look at it as glycine from connective tissue balancing out methionine from muscle tissue and therefore simulating eating the whole animal like our evolutionary ancestors did.

Calcium d-glucarate enhances glucuronidation by preventing the glucuronic acid from being pulled off of the toxin.

I think fiber is OK for daily use. You can copy the moldies and Lymies who take cholestyramine half an hour before eating so that it's in position to grab toxins in the bile as it gets secreted. If it doesn't soak up the toxins, they can be reabsorbed through enterohepatic recirculation. Activated carbon is another thing people use. I just use generic Miralax. I'm not very concerned about chronic toxins in my individual body, and Miralax cuts colorectal cancer risk in half. It's not a mechanical effect, it's a chemical effect that downregulates a growth factor.