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Hormones, receptors and anatomy; definitions and abbreviations

#3

Receptors:
* PrlR - Prolactin receptor --- contained in nipple and areola
* ER - Estrogen receptor
* ER-alpha - ERα - ER-α - Estrogen Receptor Alpha --- contained in milk ducts
* PR - Progesterone Receptor
* PRB - Progesterone Receptor B --- contained in cooper's ligaments, and mammary glands
* GHR - Growth Hormone Receptor
* CaSR - Calcium Selective Receptor --- regulates calcium for purposes of breastfeeding

Hormones:
* IGF-1 - Insulin growth-like factor 1
* Prl - Prolactin
* LH - Luteinizing Hormone
* FSH - Follicle Stimulating Hormone
* GH - Growth Hormone
* DHEA - Dehydroepiandrosterone
* Estrogens are a class of hormones.
** E1 - Estrone - oestrone
** E2 - Estradiol - oestradiol - 17β-estradiol
** E3 - Estriol - oestriol
** E4 - Estetrol
** Phytoestrogens - plant based estrogens
** Mycoestrogens - fungal based estrogens. The prefix myco means having to do with fungi. Red Reishi would contain mycoestrogens.
* The words progestin, progestogen, and progesterone are often used interchangeably in science literature.
** Progesterone - P4 - is a specific hormone.
** Progestogens are a class of hormones that include progesterone. The term progesterones, sometimes refers to all progestogens. Progestogens are not estrogens.
** Progestins often refer to synthethic progestogens.
** Phytoprogestins, phytoprogestogens and phytoprogesterones have the same meaning, they mean plant progestogens.
* Phytohormone - plant based hormone.
* Mycotoxin - toxin from fungal sources; Mycotoxin is NOT mycoestrogen. ZEN contains both mycotoxins and mycoestrogens.

Terms:
* SERM - Selective Estrogen Receptor Modulator; means it interacts with ER
* SPRM - Selective Progestin Receptor Modulator; means it interacts with PR
* Agonist - encourages activity
* Antagonist - discourages activity
* Downregulation - Reduction in receptor proteins, decreasing sensitivity to hormones
* Upregulation - Increase in receptor proteins, increasing sensitivity to hormones

Anatomy:
* Mammary glands - milk producing glands or lobules
* Cooper's ligaments - ligneous tissue that connects from the extent of the pectoral muscles, and supports the breast
* Milk ducts - ducts that transfer milk from the mammary glands to the nipple
* Areola - surrounds the nipple
* Mongomery's or Areolar glands - glands located on the areola to lubricate the nipple and areola

       

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