Good question and I doubt there is an answer out there. Even with brand new sealed bottles there are questions since this is an unregulated industry. How was the PM harvested? At what point in it's lifecycle? How long was it stored? What part of the plane was used? How old were the bottles when they were shipped to you?
Many of us has expressed concerns over the years that different batches may have different potency rates, according to all of these factors, but there is little that can be done. Without FDA oversight, there is nothing to go on other than what each company says it does... do you trust that? LOL
So, blindly we all stumble on in the dark, and hope for the best. Thankfully, even under these far less than perfect circumstances, many of us have had great results.
Sigh...
I hope that helps, honey.

Hugs