[Lotus]

Ok, not PM (sorry) but this is about progesterone for men, which some of it is surprising.

• What are the symptoms of “estrogen dominance”?
  According to John R. Lee, M.D.*, symptoms of estrogen dominance that men can experience include weight gain, bloating, mood swings, irritability, headaches, fatigue, depression and hypoglycemia. Estrogen dominance is known to contribute to cancer of prostate and the breast. It may seem paradoxical, but men are not immune to breast cancer

• When should men start using natural progesterone?
  Men can enjoy many of the non-female-specific benefits of the hormone. Dr. Lee* has recommended progesterone supplementation for men in their late forties and older, when they experience low energy or fatigue, decreased libido, have increased body fat, enlarged prostate or to want to help prevent prostate enlargement.

• Progesterone is needed to counter-balance the effects of excess estrogens. Also, by blocking the enzyme 5a-reductase (see the diagram), progesterone inhibits the conversion of testosterone to dihydrotestosterone (DHT), which is a stimulant of prostate cell growth.

• What is the dose of progesterone for men?
  It should not exceed 8 mg per day. Depending on body weight, an average daily dose is 3 - 5 mg. The dose can be single or split between morning and afternoon. Progesterone should be used for 21 to 25 consecutive days in a month and discontinued until the end of the month; the cycle is then repeated.

-Excessive long-term use of progesterone (or any other hormones) may lead to hormonal imbalance.