23-02-2014, 09:43 PM
(23-02-2014, 07:20 PM)eloise614 Wrote: PM works to modulate receptor sites/cells in various areas of our body which then work to create E. But is there a set number of receptor sites within the human body? For example, using random numbers, does each person have only 100? Or could one person have 50 while another has 150? Maybe I'll have to borrow some of my med school friend's books.
Furthermore, it seems like each person could also vary in how quick the PM receptor modulation works. If so, the question naturally follows, would there be a way to quicken such modulation?
It's funny, I was a bit of a slacker in college but not out of laziness but out of the fact that my profs usually taught verbatim from the book (which they wrote!). What's the point in lecture if I can just read the same thing when I want to and not have to get up at 8am and slug across campus? At at top 20 world university, my attitude toward class was definitely not shared by my friends and other classmates. Plus, I liked the social side of college a bit better than wasting 4 years in a library.
Eloise,

I'm not sure mow many receptor cells the human body has, I'm not sure a PhD can even tell you that. I'm more sure of how many receptors sites (target tissues) there are, 6. Below are just some quick facts that are worth repeating.
Quote: There are two types of estrogen receptors, alpha and beta. Both are structurally and functionally very similar, although can have different localizations in the human body. While both types of receptors are found in the central nervous and cardiovascular systems, breast and bone tissue, and urogenital tract, estrogen alpha is prominent in the liver and estrogen beta in the gastrointestinal tract. The reason for this is not yet known, and it is postulated that the two types of estrogen receptors may have slightly different functions depending on their position in the body.
Quote:As a result, the estrogen receptor is a complex protein that controls both intricate and delicate aspects of human growth. To understand it fully, we must continue to study its structure in complex with its many coactivator proteins and hope to learn enough from those structures to form drugs that can battle breast, uterine, and endometrian cancers more efficiently.
I suppose its easier to understand how PM activates the receptors then trying to find out how many exist. So, of the 6 target areas they are different in there responses. But again, Estradiol, progesterone and prolactin normally activate the respective receptors that cause breast growth. Remember receptors are proteins found inside cells and regulated by DNA binding.
Lol, my social agenda was my primary concern!.

