[Lotus]

Well, I'm no expert in this subject area, but something seems obvious to me.

Here's the description of 'estrogen receptor' from Wikipedia:

"Estrogen receptors are a group of proteins found inside cells. They are receptors that are activated by the hormone estrogen (17β-estradiol).[1] Two classes of estrogen receptor exist: ER, which is a member of the nuclear hormone family of intracellular receptors, and GPR30, which is a member of the rhodopsin-like family of G protein-coupled receptors. This article refers to the former (ER).

Once activated by estrogen, the ER is able to translocate into the nucleus and bind to DNA to regulate the activity of different genes (i.e. it is a DNA-binding transcription factor). However, it also has additional functions independent of DNA binding.[2]"

So the number of estrogen receptors is as many as there are cells containing the relevant proteins. That says that as breast tissue grows, the number of cells increases, so the number of receptors increases accordingly. There are literally MILLIONS of estrogen receptors in the body.

Okay, so set me straight. Where am I going off the rails?

Clara

Thanks Clara,

Glad we're embracing the science!, isn't this fascinating!

There are target tissues as I've listed, and only 2 kinds of estrogen receptors types ER-a and
ER-b,

And Estrogen does the rest-

I'll have another post about PM coming up shortly, more info to digest.