[Lotus]

A particular concern of mine is to minimize the risk of prostate cancer, as both my father and grandfather died of it. I have episodically taken DIMM thinking it might help, but grew concerned that it might be knhibiting the effect of PM. Any advice on that front will be much appreciated.

Hi spanky,

I'm so sorry to hear about you're father and grandfather, when's the last time you had yourself checked?. As far the two together it would seem like a good fit, to be sure I'd ask your PCP if you can. (I'll do more research and see what else's shakes out)



DIM is Diindolylmethane-It is an anti carcinogen and also improves estrogen metabolism. Plant-derived 3,3′-Diindolylmethane Is a Strong Androgen Antagonist in Human Prostate Cancer Cells* DIM is remarkably similar in conformational geometry and surface charge distribution to an established synthetic AR antagonist, Taken with estrogen agonist, activities of DIM are seen as an hormone disrupter. DIM is the first example of a pure androgen receptor antagonist from plants.


Dim is also considered an AA. (Estrogen agonist)-an antagonist for estrogen that is used in the treatment of breast cancer, like taking tamoxifen, which is a drug that antagonizes breast cancer cells.

Well, turns out they actually make a product with PM and Dim, said to enhance PM, which to me means the metabolism.

http://www.amazon.com/Natures-Answer-Pueraria-Mirifica-Vegetarian/dp/B003HEVFIW

Hope it helps!

I have some of this stuff and it was the first PM I ordered, I guess I should have read into the ingredients before I bought it

It has ;

Folate (usp folic acid) 200mcd 50% RDA
vitamin B12 (as cyanocobalamin) 500 mcd 8333% RDA (WTF)
biotin 150 mcd 50% rda
Selenium (as selenomethionine) 70 mcd 70% rda
Pueresterol (as Peuraria Mirifica root extract) 100 mg
DIM (di-indoylmethane) 50 mg

So not much PM but WTF why is there so much B12???

It supports you're metabolism, B12 helps the breakdown, DIM speeds up the metabolism of E through excretion.