[AnnieBL]

Ps. Thanks M for the question, sometimes I feel I'm all alone in research land!

I long ago became aware that this whole subject was horribly complicated and that few people out there (including many endocrinologists) have any real feel for it. You are rapidly becoming one of the few through a great deal of hard work and perseverance, for which we owe you a great debt. I've just tended to throw up my hands and wait for other people to give me some idea of what I should be doing.

One area in which, possibly through laziness or inattention, I finf information lacking, is that of timing and duration of some of these processes, particularly those relating to the all important receptors. Obviously 'half-life' of the things we take, even if known, is only a small part of the process.

Anyhow, thank you so much and many hugs for your labours (although it does seem that you have your own reward in your magnificent development!