04-05-2014, 08:13 PM
Yeah oral (swallowed) is how you put the biggest load on the liver. Patches are a Pain in the back side, sublingual (under the tongue) is the way to go. Some good posts off site about potency of sublingual vs. oral. One write up I saw listed potency of oral estrogens at 20-30% of the dose taken whereas sublingual was nearly 90%.
Makes me wonder if PM would follow the same model. Three times less PM for the same effect? That is if PM is processed the same way as oral estrogens are. I guess it also depends on how nasty it would be sitting under one's tongue until it was all absorbed.
Makes me wonder if PM would follow the same model. Three times less PM for the same effect? That is if PM is processed the same way as oral estrogens are. I guess it also depends on how nasty it would be sitting under one's tongue until it was all absorbed.