06-03-2015, 04:17 AM
Here's an update on some novel approaches towards aromatase.
cAMP-dependent signaling pathways (cyclic adenosine monophosphat).
COX2 inhibitors (PGE2), problematic
protein kinase A (PKA)
Free fatty acids
aromatase expression is switched to promoters I.3 and II which are transactivated by protein kinase A (PKA) and cAMP-dependent signaling pathways.
These are promoters genes for aromatase.
![[Image: attachment.php?aid=9036]](http://www.breastnexus.com/attachment.php?aid=9036)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142499/
cAMP-dependent signaling pathways (cyclic adenosine monophosphat).
COX2 inhibitors (PGE2), problematic
protein kinase A (PKA)
Free fatty acids
aromatase expression is switched to promoters I.3 and II which are transactivated by protein kinase A (PKA) and cAMP-dependent signaling pathways.
These are promoters genes for aromatase.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142499/

