[Lotus]

I'm not throughly convinced about forskolin being an aromatase promoter yet, although I wouldn't rule it out, plus....the side effects are risky . xxd announced it way back when, it was great info to say the least, although most of the links provided are down from overtime I guess?. From what I've found forkislin will intensify with E2, or with E2 and progesterone. The study below has it at 4 fold increase with the introduction of Dex (dexamethasone) which has already been shown to up-regulate aromatase.


We examined the effects of FSK on aromatase activity in SV-HFO cells. As shown in Fig. 2⇓, aromatase activity in the presence of 100 nM Dex was 3.75 pmol/mg protein per 6 h, and the addition of FSK increased aromatase activity in a dose-dependent manner. When 10 μM FSK was added, aromatase activity increased about 4-fold (15.2 pmol/mg protein per 6 h) compared with Dex alone. Aromatase activity was not up-regulated in the presence of 10 μM FSK alone. These results suggest that the up-regulation of aromatase activity by FSK depends upon Dex.


Forskolin and dexamethasone synergistically induce aromatase (CYP19) expression in the human osteoblastic cell line SV-HFO
http://www.eje.org/content/152/4/619.full


The link from xxd shows an indirect aromatase activity, meaning forskolin by itself may not work. But, when combined with E2, Progesterone or dex it up-regulates aromatase.

xxd
http://www.breastnexus.com/showthread.php?tid=11512&page=2

Assessment of chemical effects on aromatase activity using the H295R cell line.
http://www.ncbi.nlm.nih.gov/pubmed/20087668