[Patience]

That's good idea adding k2, how do you supplement it?, I tried grass fed butter in some coffee that Pom suggested, not bad. Egg yolks, gouda and brie cheese are other sources of k2 from what I've read.

That study is a good find (thanks). A healthy immune system is a big priority in NBE for sure. Mine went haywire when I pushed too hard.

ER-beta is in the bones, which is tied into NBE response elements, cancer too. I recently came across that B2 improves ER-a sensitivity.

Everything I read had Vitamin D increasing "total and free T", which imo can be a good thing since E comes from T. The androstenedione pathway converts T to E1 then to E2 and back again to E1. DHT which I understood had no value in NBE takes a exit pathway that possibly has a ER-beta link. (too funny).

It does seem odd why aromatase therapy wouldn't be included with HRT more often. Some treatment protocols for gynecomastia will include aromatase inhibitors with T therapy as a way to control runaway T. The initial supra therapeutic dosage of testosterone gets dumped into E in some cases of gyno, probably more often than not.

You can hardly find any related nbe info on pro-aromatase, when search terms are "promoter gene/expression" the yield is somewhat better, mostly it's about AI's. But here recently I think aromatase comes in many disguises , e.g. 17 beta HSD's, NAPHD (it's another enzyme), NO2 (nitric oxide), a few others too, heck I'd even call the androstenedione pathway an aromatase.

Btw, I'm glad you came out of moth balls, welcome back.

Okay, so, I read through this entire thread. I have just one question: what form of white peony would one use? I did a quick search on Google and it is available as a tea, liquid extracts, and 'immune support' capsules.

Liquid extract would obviously work best as a topical treatment, but which of the other two is better for oral administration?