Thanks LL, ha!, my C.O. was a complete nut job!.....I don't think he ever slept!
I've recently have been looking into the shaping of breasts, or Morphogenesis of Mammary glands (shaping of the breasts). Activation of ER-α causes elongation or horizontal growth of mammary duct cells.
Progesterone receptor activation causes side-branching of mammary gland cells.
Density, areolar gland development, and gland lactation development are caused by prolactin receptor activation.
Hops
From the table the effects of 8-prenylnaringenin on estrogen receptors are shown. 8-prenylnaringenin directly stimulates ER-α and the progesterone receptor in the mammary glands. It also indirectly stimulates the prolactin receptor by causing an increase in prolactin. 8-prenylnaringenin (hops) stimulates the hormone receptors responsible for breast growth possibly in elongation, area, areola and density.
I love what hops can do but its not easy to supplement with, at least for me!, imo.
Mammary gland development requires both systemic hormones and local growth factor-mediated tissue interactions. Classical hormone ablation/replacement experiments, and more-recent genetic analyses in mice, have shown that post-pubertal gland development requires systemic hormones from ovary [estrogen (E) and progesterone (P)], pituitary [growth hormone (GH) and prolactin (PRL)] and adrenal gland (glucocorticoids) (Topper and Freeman, 1980). Loss of ovarian or pituitary function leads to failure of hormone-dependent ductal elongation after puberty, with E and GH participating primarily in ductal elongation and P and PRL participating primarily in alveolar development. Glucocorticoids enhance (but are not essential for) ductal elongation and are required for alveolar function in lactation.
http://dev.biologists.org/content/136/9/1423.full
So my question was how does the breast take shape?, and this is what I found, fascinating!
I've recently have been looking into the shaping of breasts, or Morphogenesis of Mammary glands (shaping of the breasts). Activation of ER-α causes elongation or horizontal growth of mammary duct cells.
Progesterone receptor activation causes side-branching of mammary gland cells.
Density, areolar gland development, and gland lactation development are caused by prolactin receptor activation.
Hops
From the table the effects of 8-prenylnaringenin on estrogen receptors are shown. 8-prenylnaringenin directly stimulates ER-α and the progesterone receptor in the mammary glands. It also indirectly stimulates the prolactin receptor by causing an increase in prolactin. 8-prenylnaringenin (hops) stimulates the hormone receptors responsible for breast growth possibly in elongation, area, areola and density.
I love what hops can do but its not easy to supplement with, at least for me!, imo.
Mammary gland development requires both systemic hormones and local growth factor-mediated tissue interactions. Classical hormone ablation/replacement experiments, and more-recent genetic analyses in mice, have shown that post-pubertal gland development requires systemic hormones from ovary [estrogen (E) and progesterone (P)], pituitary [growth hormone (GH) and prolactin (PRL)] and adrenal gland (glucocorticoids) (Topper and Freeman, 1980). Loss of ovarian or pituitary function leads to failure of hormone-dependent ductal elongation after puberty, with E and GH participating primarily in ductal elongation and P and PRL participating primarily in alveolar development. Glucocorticoids enhance (but are not essential for) ductal elongation and are required for alveolar function in lactation.
http://dev.biologists.org/content/136/9/1423.full
So my question was how does the breast take shape?, and this is what I found, fascinating!
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