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Lotus   17-09-2014, 07:58 AM

(17-09-2014, 06:42 AM)Candace Wrote: You have not provided a legitimate answer, you're just blowing smoke in a desperate attempt to avoid having to admit that you were wrong about something.

More proof-(you blew this info off).

To evaluate the safety and efficacy of an extract of Ganoderma lucidum that shows the strongest 5alpha-reductase inhibitory activity among the extracts of 19 edible and medicinal mushrooms by a double-blind, placebo-controlled, randomized and dose-ranging study in men with lower urinary tract symptoms (LUTS).
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Ganoderma lucidum: A Potent Pharmacological Macrofungus
http://www.researchgate.net/profile/Prakash_Bisen/publication/40032434_Ganoderma_lucidum_a_potent_pharmacological

Page 722, anti-androgen activity, page 724 estrogenic activity

5α-reductase inhibition, androgen receptor binding activity, prostate cancer cell lines.
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Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms

While screening mushrooms, we discovered that ethanol extracts of G. lingzhi showed the strongest 5α-reductase inhibitory activity among 19 species of mushrooms. Furthermore, treatment with the fruit body of G. lingzhi itself, or its ethanol extracts, significantly inhibited testosterone induced growth of the ventral prostate in rats9, 10. Our group previously isolated a series of triterpenoids from G. lingzhi. These compounds suppressed the proliferation of androgen-dependent and androgen-independent prostate cancer cell lines11 and estrogen-dependent MCF-7 cells12, and inhibited osteoclastic differentiation13. Among these triterpenoids, we found that only ganoderic acid DM (1, Fig. 1) had multiple functions, such as 5α-reductase inhibition, androgen receptor binding activity, prostate cancer cell, and proliferation and osteoclast differentiation11, 12, 13, 14. Although 1 affects different signaling pathways in different cell lines and has multiple functions, we have identified its target proteins, which explain and clarify the universal mechanism of its medicinal efficacy.

http://www.nature.com/srep/2012/121130/srep00905/full/srep00905.html

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Ganoderma - a therapeutic fungal biofactory.
http://www.researchgate.net/profile/Russell_Paterson/publication/6882609_Ganoderma_-_a_therapeutic_fungal_biofactory/links/00b7d5225ef366b7c6000000?ev=pub_ext_doc_dl&origin=publication_detail&inViewer=true

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Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC-3
http://www.reishiessence.com/images/int_journal_of_oncology.pdf

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