Clelia, I've included some related papers for discussion. 
Long-chain acyl-CoA synthetases and fatty acid channeling
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846691/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846691/pdf/nihms179818.pdf
Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels
http://www.researchgate.net/profile/Thomas_Baukrowitz/publication/7005678_Cytoplasmic_accumulation_of_long-chain_coenzyme_A_esters_activates_KATP_and_inhibits_Kir2.1_channels/links/02e7e52639c9abf06e000000.pdf?ev=pub_ext_doc_dl&origin=publication_detail&inViewer=true
Targeting Intermediary Metabolism in theHypothalamus as a Mechanism to Regulate Appetite http://pharmrev.aspetjournals.org/content/62/2/237.full.pdf
Long-chain acyl-CoA synthetases and fatty acid channeling
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846691/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846691/pdf/nihms179818.pdf
Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels
http://www.researchgate.net/profile/Thomas_Baukrowitz/publication/7005678_Cytoplasmic_accumulation_of_long-chain_coenzyme_A_esters_activates_KATP_and_inhibits_Kir2.1_channels/links/02e7e52639c9abf06e000000.pdf?ev=pub_ext_doc_dl&origin=publication_detail&inViewer=true
Targeting Intermediary Metabolism in theHypothalamus as a Mechanism to Regulate Appetite http://pharmrev.aspetjournals.org/content/62/2/237.full.pdf
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