This study explains about starving fat cells for (massive) synthesis. It all ties together.

Free fatty acids: continuously released from adipose tissue, with a peak in secretion during fastting and a decrease during postprandial periods. During obesity, when resistance of adipose tissue to insulin develops (partly because of hypoxia generated following adipocyte hypertrophia/hyperplasia), enhanced lipolysis leads to a massive increase in plasma free fatty acids. Free fatty acids will then perturb liver and muscle insulin action.


Lipophilic Micronutrients and Adipose Tissue Biology
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509510/pdf/nutrients-04-01622.pdf