[Lotus]

One of the biggest questions many of us have about NBE/HRT is why it take so long for results. The answer isn't so simple, but I'll try to shed some light on the situation, (my 2 cents).

There's a balance the body tries maintain called homeostasis, and when the body detects a deficiency it sends out more signals to correct that imbalance. Now throw in NBE/HRT and the signaling process senses changes to the system, it's been accustomed to receive the same signals since birth. Changing the hormone signaling process takes time, it's gonna want to fight this change, and until the new changes can be maintained it takes time. So.......2-3 years is the typical time frame before we see significant change in terms of breast and body changes.

Here's a science example in terms what I mean. It takes up to two years for the pharma anti-androgen dutasteride before its reaches a 93% inhibition of DHT.

The saturation, cascade (release) of estrogen or (E2) is risky. Meaning excess estrogen increases the risk of heart attacks, stroke, DVT and BPH. I think if we take a straight foward approach on elimaniting DHT first, we lessen the health risks by having to saturate with E2, imo E2 should come after 5 ar inhibition. However, universal precautions are always always first. (e.g. Green Tea, omega 3's, reducing stress, sleep, diet and fitness).