I didn't mean to get you going, Lotus Okay, well maybe I did .

To add onto this: because androstenedione (or, Δ4-dione) can be converted to estrogens, people taking this supplement may have estrogenic side effects.

In addition to its role as a precursor to testosterone in the body, Δ4-dione has slight androgenic properties in its own right, acting as a weak partial agonist of the androgen receptor. However, in the presence of full agonists like testosterone or dihydrotestosterone (DHT), due to its lower intrinsic activity in comparison, it has antagonistic effects, and can behave more like an antiandrogen.