Sorry, forgot this one:
Growth hormone secretion pattern regulates hepatic gene expression. Estrogen administration converts the male intermittent growth hormone secretory pattern to a continuous secretion (40). Also, we and others (51, 63) have reported that estrogen administration, as well as gonadectomy, in male and female rats changes the levels of CYP2C11 and CYP2C12 that are markers of male and female dominant genes, respectively.
Multihormonal regulation of hepatic sinusoidal Ntcp gene expression
http://ajpgi.physiology.org/content/ajpgi/287/4/G782.full.pdf
So, I'm not talking gonad removal, just the fact that we can count on things like PM (Miro & dexyomiroestrol) and estradiol to help target these proteins in the liver and brain, along with targeting certain amounts of growth hormone (aka Pulsatile) signaling.
Growth hormone secretion pattern regulates hepatic gene expression. Estrogen administration converts the male intermittent growth hormone secretory pattern to a continuous secretion (40). Also, we and others (51, 63) have reported that estrogen administration, as well as gonadectomy, in male and female rats changes the levels of CYP2C11 and CYP2C12 that are markers of male and female dominant genes, respectively.
Multihormonal regulation of hepatic sinusoidal Ntcp gene expression
http://ajpgi.physiology.org/content/ajpgi/287/4/G782.full.pdf
So, I'm not talking gonad removal, just the fact that we can count on things like PM (Miro & dexyomiroestrol) and estradiol to help target these proteins in the liver and brain, along with targeting certain amounts of growth hormone (aka Pulsatile) signaling.
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