(16-05-2016, 11:48 PM)bobie Wrote:

(10-05-2016, 07:06 PM)Lotus Wrote:

(10-05-2016, 02:28 PM)jannet.duff Wrote: So if I read between the lines, pharma HRT effects ER-a, but PM effects ER-b. So, if I add some PM back into the mix it should assist growth rather than hinder it.

Yes E2 binds with ER-a, however!........bioidentical progesterone is still needed to complete ductal side branching (rounding). Too much prolactin produces tubular growth, while E2 produces elongation. Add in growth hormone and essential fatty acids and hopefully things start happening lol, (albeit a slow process).


I still wouldn't use PM with HrT:

Quote:miroestrol competes with estrogen and blocks the excessive stimulation of estrogen receptors often seen with breast or endometrial cancer.

How much prolactin is too much? as you may remember my levels have always been high, nearly double what the nhs would like at my last blood test

A few things stick out. Are the labs drawn at the times of the day (a few hours after waking up). I'd bet you have nil for T (or close to it, less than 25 ng/dL). Other things to look at are liver function, hypothyroidism, cirrhosis, stress, dopamine.

High prolactin could also mean you're having too much E2 in an HrT program.