[Lotus]

Only in male-to-female transsexuals in whom progestative chemical castration is combined with feminising estrogen therapy will full acini and lobular formation occur. Hence, combined progestative anti-androgens and estrogens is necessary for the genetically male breast to mimic the natural histology of the female breast.[



How important all of this is to optimal feminisation remains unclear and likely varies from individual to individual. What is clear is that Progestogens do play an important part in, among other things, proper breast development. Given that, and the lack of any compelling reason not to use them, it seems clear that a Progestogen should be a part of any optimal MTF HRT regimen.

Without progesterone breasts lose the chance to look female, progesterone cream helps to round breasts (and cancer prevention too).