Also.....glucocorticoids rapidially induce nuclear localization of the glucocorticoid receptor, (when 17beta estradiol is introduced together with glucocorticoids localization occurs in minutes) as did cAMP (second messengers) and E2 synthesis occurs in 15 minutes.

So...what are glucocorticoids types?, prednisone, dexamethasone, and hydrocortisone etc. long term use is dangerous, I'm not suggesting this. My thought is that an anti-inflammatory action inside receptors can speed up its signal to synthesize. To this extent, I'm on the look-out for something to complete this cascade.


Anti-inflammatory actions of glucocorticoids: molecular mechanisms.
http://www.ncbi.nlm.nih.gov/pubmed/9854452