[jannet.duff]

Is this something specific to the PM, or is this just happening indirectly by raising Estrogen?

I'm not able to transition now, but I wanted to get a prescription for E after hearing about the mental effects. I can't get the Rx now so I'm trying the OTC stuff. So far haven't had any results and was scared to try PM after reading about the DVT risk, but that might be indirectly due to raising E also (?)

The mental benefits are from raising estrogen levels.
DVT risk can be eliminated by taking Rutin. 
Injectable estrogen gived you the same DVT risk as a genetic female with her own estrogen.