05-04-2018, 03:04 PM
Think it's a bit of the old caviat of YMMV. I see the way some are almost transformed, yet others... not so much.
Reduction of muscle mass and loosening of tendons does seem to be given though, even if it might take a while and may vary in degree.
However, I have noticed a steady trickle of anecdotal experience of bones being affected over time too. I realise established wisdom is that bone isn't affected by HRT, but there are hormone receptors in bone and our entire bone structure is replaced every ten years. So it's perhaps not unreasonable that over time there may be some changes even here?
However, it seems more clear that adjusting our hormones can also trigger underlying health and genetic issues. Which I suppose makes sense as hormones are one of the main ways the body regulated itself, so getting the big stick and waggling it about in our endocrine system is going to stir things up a bit. So perhaps a lesson to take from this is to understand ourselves better and keep aware of any changes or untoward symptoms?
Reduction of muscle mass and loosening of tendons does seem to be given though, even if it might take a while and may vary in degree.
However, I have noticed a steady trickle of anecdotal experience of bones being affected over time too. I realise established wisdom is that bone isn't affected by HRT, but there are hormone receptors in bone and our entire bone structure is replaced every ten years. So it's perhaps not unreasonable that over time there may be some changes even here?
However, it seems more clear that adjusting our hormones can also trigger underlying health and genetic issues. Which I suppose makes sense as hormones are one of the main ways the body regulated itself, so getting the big stick and waggling it about in our endocrine system is going to stir things up a bit. So perhaps a lesson to take from this is to understand ourselves better and keep aware of any changes or untoward symptoms?

