[PaulaJ]

I was up to .5ml of injected depo-estradiol once weekly, and still no effects. He refused to raise it higher because I am a smoker. No I am not yet ready to quit, sorry but current stress levels don't allow me to.

You'd really rather quit HRT than quit smoking?

I'm not saying it's not hard, but smoking makes E less effective. 

No one else is saying it, but that is your choice, smoking or the woman in the picture.