09-02-2020, 06:24 PM
(This post was last modified: 09-02-2020, 07:43 PM by VergeOfDiscovery.)
One thing to consider in the arsenal is Oleuropein from Olive Leaf Extract.
This stuff is deadly to just about every nasty one can think of (and think of the very worst things out there), but in a test tube.
There have been attempts to patent this stuff but they couldn't quite nail things down.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002804/
Scroll down to the sections on Antimicrobial and Antiviral activity that touch on Staphylococcus, Salmonella, Bacillus, pneumoniae, Ecoli, mono, hepatitus, rotovirus, rhinovirus, influenza, HIV, etc.
Also, see here where it is mentioned in connection with Coronavirus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790717/
It's not a magic bullet, but there's tons of research on its potential.
My understanding from prior research on this subject is that, in layman's terms, it somehow "rips the jackets off" (compromises membrane integrity) the cells of the invaders so they simply fall apart.
Olive trees go back as far as 40 million years (https://en.wikipedia.org/wiki/Olive) and it's possible they have evolved to fight off things detrimental to their survival, and in turn, provide a potentially leverageable benefit (even if not perfected as yet).
Interestingly, Miltefosine, which has been used successfully to treat Naegleria fowleri (brain eating amoeba), seems to work by a similar action: Miltefosine exerts its activity by interacting with lipids, inhibiting cytochrome c oxidase and causing apoptosis-like cell death.[22] This may affect membrane integrity and mitochondrial function of the parasite
https://en.wikipedia.org/wiki/Miltefosine
It also appears to share a similar laundry list of baddies it may be impactful against.
My own curiosity in this is particularly focused on "mechanism of action."
This stuff is deadly to just about every nasty one can think of (and think of the very worst things out there), but in a test tube.
There have been attempts to patent this stuff but they couldn't quite nail things down.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002804/
Scroll down to the sections on Antimicrobial and Antiviral activity that touch on Staphylococcus, Salmonella, Bacillus, pneumoniae, Ecoli, mono, hepatitus, rotovirus, rhinovirus, influenza, HIV, etc.
Also, see here where it is mentioned in connection with Coronavirus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790717/
It's not a magic bullet, but there's tons of research on its potential.
My understanding from prior research on this subject is that, in layman's terms, it somehow "rips the jackets off" (compromises membrane integrity) the cells of the invaders so they simply fall apart.
Olive trees go back as far as 40 million years (https://en.wikipedia.org/wiki/Olive) and it's possible they have evolved to fight off things detrimental to their survival, and in turn, provide a potentially leverageable benefit (even if not perfected as yet).
Interestingly, Miltefosine, which has been used successfully to treat Naegleria fowleri (brain eating amoeba), seems to work by a similar action: Miltefosine exerts its activity by interacting with lipids, inhibiting cytochrome c oxidase and causing apoptosis-like cell death.[22] This may affect membrane integrity and mitochondrial function of the parasite
https://en.wikipedia.org/wiki/Miltefosine
It also appears to share a similar laundry list of baddies it may be impactful against.
My own curiosity in this is particularly focused on "mechanism of action."