[thegirl1951]

Thank you that's great will search that today

The general recommendation for drugs is to take the minimum amount to accomplish the task/goal/result.  If 250 mg of PM works, maybe try a lower dose and see if that works.  If a lower dose, maybe 25% less, works, then maybe try 50%, i.e., 125 mg.  The lower the dose that gives you the desired result, the less chance you will have undesirable side effects.