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Lotus   15-09-2022, 03:47 AM
Hi Mel, 

Great to chat with you again, that bitterness is called " Theobromine " and despite its annoying aftertaste it does have its purpose…even for breast enlargement. You'll find Theobromine in coffee, tea, dark chocolate and trace amounts in white chocolate. I'm attaching a wiki link that describes additional benefits. But the one benefit for nbe from theobromine comes from the fact it inhibits PDE (phosphodiesterase). Anytime you inhibit PDE inside the cytoplasm magical things happen ? for our nbe purpose it aids in breast growth. 
 
Quote
The cyclic nucleotide phosphodiesterases comprise a group of enzymes that degrade the phosphodiester bond in the second messenger molecules cAMP and cGMP. They regulate the localization, duration, and amplitude of cyclic nucleotide signaling within subcellular domains. PDEs are therefore important regulators of signal transduction mediated by these second messenger molecules. 
End science quote. 

Imo, if PDE's aren't inhibited in the cytoplasm then estrogen metabolism becomes increasingly inefficient, lol a conversion for another day. ?

PDE4-Mediated cAMP Signaling 
https://pubmed.ncbi.nlm.nih.gov/29385021/
Phosphodiesterase
https://en.m.wikipedia.org/wiki/Phosphodiesterase

Btw Mel, I love both: white chocolate and dark chocolate

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