04-12-2023, 06:42 PM
Hi Mel, and a belated welcome to BN. 
I disagree that 200mg of progesterone per breast is too high. Science literature indicates that progesterone application only yields about 10% absorption rate, progesterone gel gets a higher bioavailability than progesterone cream. When I first started using progesterone capsules on my breasts I gained 4 inches of growth during the first month. During that time (the month period) I was only using progesterone topically, the second month I used DHEA cream. I posted my lab results after that month period of using P4 (progesterone), you can review those results in the X-thread.
Progesterone cream (PC) isn't quite the strength of P4 (obviously). P4 increases ductal side branching (lobuloalveolar ducts) while E2 increases epithelial cells.. or, boob cells and growth.There's a difference between what E2 is measured in blood vs E2 in peripheral tissue (as in breasts). When we try to go after lactation we lose E2 in the breasts, thus breast changes occur (or loss of breast volume). From my research, I think if you use P4 and E2 (the topical program) it should be a 2:1 ratio favoring P4. The reason for this is P4 lowers E2 epithelial cells. But, what topical P4 does is add more fat to breasts (scientifically verified). There's a ton of research studies on progesterone and mammary epithelial cells (MEC’s) which I'll be sharing in the X-thread coming real soon. One other thing, P4 has a back door pathway to DHT, so I take Bicalutamide. My DHT was <5 ng/dL (which is nonexistent)... that's with my progesterone being high at 2.5 ng/mL and the reference range of (.2 to 1.2) ng/mL. My E2 was 240 pg/mL. I would test your DHT. I'm attaching this for a deeper dive into the back door androgen pathway.
Classic and backdoor pathways of androgen biosynthesis in human sexual development
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260366/
Finally, your tuberous breasts are referred to as IGT (insufficient growth tissue) imo comes from a higher prolactin exposure. I had articles (in the ladies forum @ Breastnexus) that covered the IGT phenomenon, I'd have to look at that info to offer more insight. I think your breasts look lovely at your current development. I'm not convinced pumping is a good option for you until your breasts mature (and P4 helps the breasts mature).
If it were me, I'd discontinue the following:
Sunflower lecithin
Pygeum
Shatavari
If you're doing topical P4 I'd skip the rectal use until you take a break from the topical applications. If anything, you can alternate P4, DHEA and E2 to see what works best for you.
Good luck with the program.
Lotus
I disagree that 200mg of progesterone per breast is too high. Science literature indicates that progesterone application only yields about 10% absorption rate, progesterone gel gets a higher bioavailability than progesterone cream. When I first started using progesterone capsules on my breasts I gained 4 inches of growth during the first month. During that time (the month period) I was only using progesterone topically, the second month I used DHEA cream. I posted my lab results after that month period of using P4 (progesterone), you can review those results in the X-thread.
Progesterone cream (PC) isn't quite the strength of P4 (obviously). P4 increases ductal side branching (lobuloalveolar ducts) while E2 increases epithelial cells.. or, boob cells and growth.There's a difference between what E2 is measured in blood vs E2 in peripheral tissue (as in breasts). When we try to go after lactation we lose E2 in the breasts, thus breast changes occur (or loss of breast volume). From my research, I think if you use P4 and E2 (the topical program) it should be a 2:1 ratio favoring P4. The reason for this is P4 lowers E2 epithelial cells. But, what topical P4 does is add more fat to breasts (scientifically verified). There's a ton of research studies on progesterone and mammary epithelial cells (MEC’s) which I'll be sharing in the X-thread coming real soon. One other thing, P4 has a back door pathway to DHT, so I take Bicalutamide. My DHT was <5 ng/dL (which is nonexistent)... that's with my progesterone being high at 2.5 ng/mL and the reference range of (.2 to 1.2) ng/mL. My E2 was 240 pg/mL. I would test your DHT. I'm attaching this for a deeper dive into the back door androgen pathway.
Classic and backdoor pathways of androgen biosynthesis in human sexual development
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260366/
Finally, your tuberous breasts are referred to as IGT (insufficient growth tissue) imo comes from a higher prolactin exposure. I had articles (in the ladies forum @ Breastnexus) that covered the IGT phenomenon, I'd have to look at that info to offer more insight. I think your breasts look lovely at your current development. I'm not convinced pumping is a good option for you until your breasts mature (and P4 helps the breasts mature).
If it were me, I'd discontinue the following:
Sunflower lecithin
Pygeum
Shatavari
If you're doing topical P4 I'd skip the rectal use until you take a break from the topical applications. If anything, you can alternate P4, DHEA and E2 to see what works best for you.
Good luck with the program.
Lotus