I am far from the foremost expert in the matter, but after reading quite much about anatomy I am pretty sure about a few things:
1) You don't reach colon easily through your anus because there is first a longish piece of rectum (about 4 3/4 inches, or 12 cm)
2) Absorption from rectum isn't very fast, it is not designed to be for that.
3) The capsule shell will likely not even dissolve there
If you want to use the "back door route" I believe the result could be best if you mix the powder from capsule to some suitable low-temperature melting fat, such as coconut oil, and form that into some sort of suppository and insert it quite deep.
Also, there are claims that the bio-availability taken rectally is larger than by oral route, so smaller amounts are needed for same effect.
I would like to advise you to search more information before experimenting. There are at least some discussions about this method even on this board
-Teddy
1) You don't reach colon easily through your anus because there is first a longish piece of rectum (about 4 3/4 inches, or 12 cm)
2) Absorption from rectum isn't very fast, it is not designed to be for that.
3) The capsule shell will likely not even dissolve there
If you want to use the "back door route" I believe the result could be best if you mix the powder from capsule to some suitable low-temperature melting fat, such as coconut oil, and form that into some sort of suppository and insert it quite deep.
Also, there are claims that the bio-availability taken rectally is larger than by oral route, so smaller amounts are needed for same effect.
I would like to advise you to search more information before experimenting. There are at least some discussions about this method even on this board
-Teddy