[randicd1023]

I've never heard of leg cramps being a thing with HRT, at least not with bioidentical stuff we use today. It could be DVT symptom, especially when taking phytoestrogens or synthetic estrogen or progestins or taking estrogen orally. Lowering dosage or taking a break would be the smartest move to consider.

The doctor I’ve been working with supplied me with an informed consent to review and sign before starting HRT. One of the listed side effects were leg cramps and the possibility of clots.  Most of the consent outlined symptoms very similar to PM. I think I’m going to make the switch soon.