Sweets, why not ask me?... it is my recommendation, no? (it's cool though). There's more to this variable method I described of alternating E2 cream , meaning for some people who might be estrogen dominant the every other day usage would limit the over exposure of estradiol to help balance estrogen dominance.

There's another situation when women are given antibiotics to eliminate bacteria and the antibiotics end up eliminating good (and bad) bacteria. And in that scenario (any) bacteria in the vagina accelerates yeast infections. Adding topical estradiol stops the yeast infection within 5 days or so. More info to follow.