Congrats on starting HRT.   Spiro will tank your T levels so get ready to be tired and because it is a diuretic, get ready to pee a lot!  Both are good signs it’s working.  Enjoy the ride of Estrogen.  Don’t drop all NBE items though.  I’ve found Omega 3, D3, B6, Forskolin, and L-arginine to all really help support my HRT.