[DruLactin]

Think about my suggestion, it isn't expensive.
A Vial of EEn , 50 €, Last for 15 months and the NBE Stuff is even great for healthy living, 
The risk doing something bad is less, your Body tells you the direction.
Go Into it and make your decision when you will reach your Goals...
You will regret it later not trying,cause there are ever thoughts in your head...

I wanna say that its quite possible they wouldn't regret not trying it and they shouldn't feel pressure to hurry while they have time. though i will say starting in one's 40s is a great deal better than starting in ones 50s.

But yeah, Estradiol will always have a fair amount fewer side effects. PM has a risk of DVT, though if you live actively and eat well your risk is quite low at reasonable doses. the claims the BO does like irreparable feminization is mostly false, some people have significant effects far beyond what they initially planned and some people get nothing at all. The only permanent thing about it is that it might hang around in fat or something for a bit longer than some other source. So it's not like a one-way train to girl town, it's a car that's due for new brake pads, and the variance is how fast the car goes. Estradiol is def very controllable and its very strong.

-Aria