19-04-2012, 01:44 AM
SarahSchilling said:
'Sterility,Shrinkage, and/or erectile disfunction.
And if you wanted to fully transition, I've read that you may not have enough scrotum skin to make into vaginal lining.
I figure no matter what your thoughts are on changing gender, there are definitely drawbacks from long term use of anti-androgens.'
A serious antiandrogen like spironolactone can indeed have serious results. I was precsribed it for resistant hypertension, but after 18 months I have all the results in the first line of the quote, although while I think that my testicles have shrunk and my penis has definitely shrunk considerably, I don't think that either epidydimis has shrunk nor the scrotum. Although never very hairy, I have lost most of my body hair apart from reduced under arm and pubic hair and a minimal amount left on my chest, and my eyebrows are also greatly reduced. My scalp hair was largely gone already but spiro's reported side effect as a hair restorer has not kicked in. While some of these changes are not unwelcome, and I am sure it helped kick start my present NBE effort, I do not intend to transition and would certainly like to regain my male function if irreparable damage is not already done. My current prescription for spiro ran out today and I am not presently intending to renew it.
Since the spiro did help my BPH somewhat and although I am still taking the terazosin (Hytrin) that was actually prescribed for it (with limited effect like most of the established and expensive BPH drugs), I shall restart SP to compensate together with beta-sitosterol, both of which are supposed to inhibit conversion of testosterone to DHT. Neither I think blocks the action of testosterone itself (if I have any significant amount of it left in my body). Since the amount of beta-blocker (also prescribed for hypertension and a noted enemy of male function) that I was taking has already been cut by 75% with the unexpected result of subtantially reducing both my average blood pressure (to the verge of hypotension) and the variations in it, I am hoping I can get off the remaining 25% and maybe regain some functionality, particularly if I can have the Hytrin changed to daily low dose Cialis which was recently approved in the US as a BPH treatment as well as its better known application.
I have not encountered any breakouts with PM or SP but thankfully have never been very prone to that problem.
'Sterility,Shrinkage, and/or erectile disfunction.
And if you wanted to fully transition, I've read that you may not have enough scrotum skin to make into vaginal lining.
I figure no matter what your thoughts are on changing gender, there are definitely drawbacks from long term use of anti-androgens.'
A serious antiandrogen like spironolactone can indeed have serious results. I was precsribed it for resistant hypertension, but after 18 months I have all the results in the first line of the quote, although while I think that my testicles have shrunk and my penis has definitely shrunk considerably, I don't think that either epidydimis has shrunk nor the scrotum. Although never very hairy, I have lost most of my body hair apart from reduced under arm and pubic hair and a minimal amount left on my chest, and my eyebrows are also greatly reduced. My scalp hair was largely gone already but spiro's reported side effect as a hair restorer has not kicked in. While some of these changes are not unwelcome, and I am sure it helped kick start my present NBE effort, I do not intend to transition and would certainly like to regain my male function if irreparable damage is not already done. My current prescription for spiro ran out today and I am not presently intending to renew it.
Since the spiro did help my BPH somewhat and although I am still taking the terazosin (Hytrin) that was actually prescribed for it (with limited effect like most of the established and expensive BPH drugs), I shall restart SP to compensate together with beta-sitosterol, both of which are supposed to inhibit conversion of testosterone to DHT. Neither I think blocks the action of testosterone itself (if I have any significant amount of it left in my body). Since the amount of beta-blocker (also prescribed for hypertension and a noted enemy of male function) that I was taking has already been cut by 75% with the unexpected result of subtantially reducing both my average blood pressure (to the verge of hypotension) and the variations in it, I am hoping I can get off the remaining 25% and maybe regain some functionality, particularly if I can have the Hytrin changed to daily low dose Cialis which was recently approved in the US as a BPH treatment as well as its better known application.
I have not encountered any breakouts with PM or SP but thankfully have never been very prone to that problem.