[Misty0732]

I also massaged before on high doses of PM, although there were many times where I could skip massaging altogether while PM did it's job .. then again I was taking ridiculously high doses at the time too and had the most shocking event in my life happen where I couldn't remember how to speak my native language or put thoughts into words/sentences or remember people's names, and creeping numbness electrifying my body distorting my vision entirely.

Whoa, Dargona! That sounds more serious than estrogen dominance. And the fact that symptoms seem to start now on much lower PM more likely indicates a possible issue with your liver.

The fact that you were taking such large doses at one time also supports that theory. It is possible for the liver to build up a toxicity to substances that it has to process (that toxicity is called "chemical hepatitis"). It's the same mechanism that causes liver issues for habitual alcoholics and can eventually lead to cirrhosis of the liver.

I have seen this before, not with PM but with niacin (which is just vitamin B3). Some people use niacin to help lower cholesterol. It does work, but too much (2000 to 3000 mg/day) over time and the liver develops the toxicity, which in turn leads to the elevated enzymes and symptoms like memory loss, disorientation, dizziness, and slurred speech. Once the toxicity develops even much lower doses brings the symptoms on. The toxicity appears to be permanent, unfortunately.

I'm only mentioning this because the damage can be fatal if the warnings aren't heeded. The good news is the liver is very resilient and so long as one refrains from ingesting the substance the chances are good you will not suffer any other permanent issues. If you keep taking it, though, and if it is your liver, you will probably find yourself on a transplant list.

There is a fairly simple way to be sure. Take some PM in the evening (not enough to cause severe symptoms) and then have your blood tested in the morning. Specifically ask for liver enzymes. This is a VERY common test these day as some people have this problem with the popular statin drugs (like Lipitor).

I truly hope that's NOT it, but the symptoms you describe go way beyond the normal complaints around e-dominance.

Best,

Misty