04-05-2013, 02:10 AM
(03-05-2013, 01:13 PM)aleah Wrote: Also I do believe some people do get a strong response to PM due to sensitive estrogen receptors.. because it is very similar to the active form of estrogen, ethinyl estradiol. Which is what is prescribed in HRT too often (sometimes just oestradiol though) and similar reactions happen too.
I just want to point out that ethinyl estradiol is NOT the active form of estrogen naturally occurring in humans. It is the first orally active semisynthetic steroidal estrogen, and was first synthesized in 1938. (http://en.wikipedia.org/wiki/Ethinyl_estradiol)
It is a very potent form of synthetic estrogen, but is extremely nasty stuff, at least in terms of its side effects. It should be avoided at all cost. Among other deleterious side effects, this is from a long-term study of MTF transexuals published in 2011:
Quote:Current, but not past ethinyl estradiol use was associated with an independent threefold increased risk of cardiovascular death.http://www.eje-online.org/content/164/4/635.full.pdf
If a physician is still prescribing this for transition, you would be well advised to find another doctor.