[myboobs]

Here's the techno stuff, this study is a complete breakdown of how effective green tea is, I'll also provide additional info/pics etc, related to GT.

http://www.sciencedirect.com/science/art...1714000056
New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate ☆

Highlights
•
Many biological actions of EGCG are mediated by specific mechanisms other than its well-known anti-oxidant properties.
•
EGCG is a pro-oxidant per se in some biological contexts.
•
EGCG directly interacts with cell surface membrane proteins and specific known receptors.
•
Treatment of cells with EGCG regulates specific intracellular signaling pathways and transcription.
•
Specific biological actions of EGCG are regulated in a concentration-dependent manner.
Abstract
Green tea is rich in polyphenol flavonoids including catechins. Epigallocatechin 3-gallate (EGCG) is the most abundant and potent green tea catechin. EGCG has been extensively studied for its beneficial health effects as a nutriceutical agent. Based upon its chemical structure, EGCG is often classified as an antioxidant. However, treatment of cells with EGCG results in production of hydrogen peroxide and hydroxyl radicals in the presence of Fe (III). Thus, EGCG functions as a pro-oxidant in some cellular contexts. Recent investigations have revealed many other direct actions of EGCG that are independent from anti-oxidative mechanisms. In this review, we discuss these novel molecular mechanisms of action for EGCG. In particular, EGCG directly interacts with proteins and phospholipids in the plasma membrane and regulates signal transduction pathways, transcription factors, DNA methylation, mitochondrial function, and autophagy to exert many of its beneficial biological actions.

I got the drift of what lotus has said , mostly gone ove the head
I wondere how come we have so many techy guys here ?? I am from electronoc harware side and done little bit of programming in basic and cobol . Done constuction , car mechanic and at present running retail business none of which goes over my head !! But to try do understand lotus's info I get brain freez

[Lotus]

Lol, perhaps I'm just a boob mechanic

[myboobs]

Lol, perhaps I'm just a boob mechanic

Yes sirrriii , I will roll with that
Lotus if you need any business planning / set up / loan project report / profitability plaNning you know where to come

[Lotus]

Lol, perhaps I'm just a boob mechanic

Yes sirrriii , I will roll with that
Lotus if you need any business planning / set up / loan project report / profitability plaNning you know where to come

Ok cool, and thanks, (I'll defo be talking to my new financial planner, you!) I do need a good tax preparation, Uncle Sam wants mo money.

[ElainMoria]

Lol, perhaps I'm just a boob mechanic

You should SOOO Change your user title to: Boob Mechanic

That would be awesome to see considering how much great information you post that is so helpful for everyone.

~Elain

[Lotus]

Some important other facts about GT, I'm just in amazement of this study tbh, I mean who knew green tea had this much potential. Imo it was a minor supplement, and it had no real NBE value.

EGCG-activated eNOS pathways that improve cardiovascular function and anti-cancer effect in the presence of PDE5 inhibitor

Intracellular signaling pathways
In cell culture, the majority of [3H]–EGCG is found in the cytosolic fraction [34]. This suggests that biological actions of EGCG may occur through EGCG metabolites or interaction with intracellular molecules. As mentioned above, EGCG produces low level reactive oxygen species, including hydrogen peroxide that may act as a second messenger for downstream signaling pathways [23], [36], [64], [97] and [121]. This action may be mediated by direct chemical reactions of EGCG with compounds at the cell surface. However, additional unknown receptor-mediated signaling pathways cannot be excluded. EGCG also increases other intracellular second messengers including Ca2+, cAMP, and cGMP.

DNA methylation
EGCG has epigenetic functions in chromosomes [25]. Aberrant methylation on CpG islands cause gene silencing that leads to altered cellular physiology and cell proliferation. EGCG inhibits DNA methyltransferase (DNMT) which reverses methylation-induced gene silencing by directly binding to DNMT with an IC50 of less than 1 μM EGCG [26]. This suggests that EGCG is transported to the nucleus. Although this function of EGCG has been known for a decade, the specific genes affected by this mechanism are not well defined and this area requires further investigation.

Recent molecular, cellular, and animal studies have begun to reveal detailed mechanisms linking drinking green tea and life-style adjustment with prevention of chronic diseases including cancer, diabetes, and cardiovascular disorders. Furthermore, chemical modification of an EGCG pharmacophore may modify relative therapeutic activities so that combinatorial supplementation may synergistically enhance beneficial health effects [8] and [30].

[ElainMoria]

Lol, perhaps I'm just a boob mechanic

Yes sirrriii , I will roll with that
Lotus if you need any business planning / set up / loan project report / profitability plaNning you know where to come

Ok cool, thanks. I do need a good tax preparation, Uncle Sam wants mo money.

Oh but Tax preparation is easy. Open your Bank account and let the IRS take it all. Done. *nods wisely and points to empty bank account* They are always happy to take your money, not so willing to give it back. lol

[Lotus]

so true Elain, isn't it a slogan on some bureaucrat's wall about always keeping the little guy down. oh, thanks for the suggestion, I needed a change, frankly I was bored with the old handle. oh I changed my mind

Anyways, I'll stop for now where I started originally, only I left part of it out in the beginning post, there's still much more, that's enough for now.

Hey my BN friends, there's a ton info to which I'm about to share, my goal is to keep it reasonably user friendly (I'll do my best not to loose yah).

We all have an idea what makes breast growth possible, so no need go into detail there. What optimizes breast growth can be somewhat of a mystery, I think I have some solutions, or strategies that can help. You'll see how inflammation, oxidative stress, circulation, fat metabolism/diet, bioavailability of hormones will be key in the areas of improvement for increasing breast growth. At the bottom is green tea, however I'd like to start with this underrated phenomenon of NBE.

1) relieving oxidative stress/inflammation
2) knowing your metabolism/oxidative type
3) building/transforming adipose (fat metabolism)
4) increasing blood oxidation (oxygenating the blood)
5) improving the bioavailability of hormones
7) the oil rub technique
8) free radicals
9) antioxidants
10) green tea

__________________________

1) relieving oxidative stress/inflammation
Oxidative stress, inflammation, and cancer: how are they linked?
http://www.ncbi.nlm.nih.gov/pubmed/20840865/

2) knowing your metabolism/oxidative type

What Is Oxidative Metabolism?
http://www.wisegeekhealth.com/what-is-ox...bolism.htm

The blood sugar diet
http://www.totalweightlosscenter.com/for...r_Diet.pdf

Balanced Oxidizer Diet
http://www.livestrong.com/article/315489...izer-diet/

http://www.drkaslow.com/html/fast_oxidizer_diet.html
3) building/transforming adipose (fat metabolism)

Introduction to Adipose Tissue (stem cell research)

http://themedicalbiochemistrypage.org/ad...tissue.php

4) increasing blood oxidation (oxygenating the blood)
Foods to Increase the Oxygen in the Blood
http://www.livestrong.com/article/344130...the-blood/

5) improving the bioavailability of hormones
Bioavailability: How the Nutrients in Food Become Available
http://www.healthguidance.org/entry/6265...odies.html

4 Serum bioavailability of sex steroid hormones
http://www.sciencedirect.com/science/art...5X8680024X
Serum bioavailability of sex steroid hormones.
http://www.ncbi.nlm.nih.gov/pubmed/3521955

6) the oil rub technique

See entry post 1181 & 1182

7) free radicals

Free-radical theory of aging
http://wikipedia.org/wiki/Free-radical_theory_of_aging

8) antioxidants

http://wikipedia.org/wiki/Antioxidant

[myboobs]

Lol, perhaps I'm just a boob mechanic

Yes sirrriii , I will roll with that
Lotus if you need any business planning / set up / loan project report / profitability plaNning you know where to come

Ok cool, and thanks, (I'll defo be talking to my new financial planner, you!) I do need a good tax preparation, Uncle Sam wants mo money.

Tax preparation !
Don't even go there I got accountant to do all my books / wages / tax

[froger]

I couldn't resist with all this tax talk