[tanysquirrel]

Norepinephrine

purpose : arousal/ & weight loss(read whole article an effects in brown adipose tissue)

available on Amazon (14.99/bottle)

"The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rises during wakefulness, and reaches much higher levels during situations of stress or danger, in the so-called fight-or-flight response. In the brain, norepinephrine increases arousal and alertness, promotes vigilance, enhances formation and retrieval of memory, and focuses attention; it also increases restlessness and anxiety. In the rest of the body, norepinephrine increases heart rate and blood pressure, triggers the release of glucose from energy stores, increases blood flow to skeletal muscle, reduces blood flow to the gastrointestinal system, and promotes voiding of the bladder and large intestine"
https://en.wikipedia.org/wiki/Norepinephrine

"Adderall, or amphetamine, works by increasing the release of norepinephrine from cells that produce it. Dopamine is required to form norepinephrine as it is a precursor in its synthesis. As Adderall increases the release of norepinephrine, more dopamine must be converted into NE to replace the supply. This causes a decrease in dopamine. Dopamine normally inhibits prolactin and prolactin normally inhibits gonadotropin releasing hormone (GnRH). When dopamine decreases, this causes a DISinhibition of prolactin. The increase in prolactin dramatically inhibits GnRH levels. GnRH normally produces LH and FSH, which increase testosterone and spermatogenesis respectively.

"In summary...
increased NE release-->depletes DA levels-->DISinhibiting prolactin-->inhibiting GnRH--> decreasing LH and FSH--> and decreasing testosterone levels " -http://www.steadyhealth.com/topics/does-adderall-shrink-your-penis-how-long-afterwards-does-a?page=1

update : could not edit original post on norepinephrine. so I had to repost it.

Apparently Adderall upregulates norepinephrine, and will lead to gonadal atropy ( yippie for those of us who want it ) . *if * you decide to use this, I would suggest it be applied topically, since it is considered a vasoconstrictor (makes veins smaller), don't know how it would affect overall body if taken internally. wait, yes I do ,...see original post above .. use at own risk...

[Katana]

Soooo much info!
Awesome work Squirrel! and thanks <3

[tanysquirrel]

Cinnamon

Hormone regulator :
http://bembu.com/cinnamon-benefits
See particularly this passage from above link :
"Cinnamon acts to lower the amount of testosterone produced by women, while increasing the amount of progesterone.

Again, it is the cinnamaldehyde that is responsible for this benefit. This occurs naturally in cinnamon and gives it its distinctive color and aroma.

The cinnamon factor: Cinnamon can act as a hormone balancer when taken in the right amounts. To get these benefits of cinnamon you’ll need to take it as a supplement, as it requires larger doses than just sprinkling it on food."

more research needed.

[tanysquirrel]

Cardamom

digestive, hormone regulator

http://www.dreliaz.org/its-all-in-your-g...digestion/

"Chinese Cardamom: Offers numerous benefits for digestion, increases antioxidant levels and boosts immunity. Also helps to combat unhealthy cellular growth and balance hormones with the compound Indole-3 Carbinole"

more research needed.

[tanysquirrel]

Clary Sage

estrogenic

http://roberttisserand.com/2010/04/is-cl...strogenic/

pituitary stimulator:

http://heritageessentialoils.org/Fertility.html
"CLARY SAGE – stimulates pituitary gland which produces estrogen, uterine tonic, powerful with Geranium"

hormone regulator :
http://www.newmoonessentials.com/apps/bl...rmonal-oil

more research needed

[tanysquirrel]

Foods that increase HGH (human Growth Hormone). Of particular interest, Pinapple consumed just BEFORE bedtime increases and stimulates growth hormones...

"#1 Pineapple

The Journal of Clinical Endocrinology says that pineapple increases your HGH levels if you eat it just before bed. That’s because it is packed with natural substances that aid in releasing melatonin and serotonin throughout the night, which in turn, stimulates HGH production. Pineapple also stimulates production of testosterone, which is an added benefit."

http://hgh.us.com/13-foods-to-increase-h...urally.php

other supporting sites :
http://www.hghgurus.com/facts/best-hgh-b...ucts-exist

http://www.anabolicmen.com/foods-that-in...naturally/

[Lotus]

Foods that increase HGH (human Growth Hormone). Of particular interest, Pinapple consumed just BEFORE bedtime increases and stimulates growth hormones...

"#1 Pineapple

The Journal of Clinical Endocrinology says that pineapple increases your HGH levels if you eat it just before bed. That’s because it is packed with natural substances that aid in releasing melatonin and serotonin throughout the night, which in turn, stimulates HGH production. Pineapple also stimulates production of testosterone, which is an added benefit."

http://hgh.us.com/13-foods-to-increase-h...urally.php

other supporting sites :
http://www.hghgurus.com/facts/best-hgh-b...ucts-exist

http://www.anabolicmen.com/foods-that-in...naturally/

Squirrel, thanks for the research, I found pineapple acts as a second messenger, also 5 alpha reductase inhibitor (according to dr. Duke). http://www.breastnexus.com/showthread.php?tid=17436&pid=159358&highlight=Pineapple#pid159358


But, I think it would great for post workout routine, MSM is another post work out suppelment that boosts HGH.

If second messenger are still new to you (or complicated) it's worth learning more about them. How would (does) second messenger fit into NBE?........I'd start with hormone biosynthesis, which in layman's term goes something like this.

1) cell diffusion (hormones passes through the cell membrane)
2) picks up the second messager
3) second messenger moves into the nucleus
4) completion (synthesis) of DNA (activation) —> new growth..........(aka-boob growth)

Now, I've passed over several key points of synthesis, but, hopefully you get the idea.

Second messengers are:

Forskolin
Calcium

A couple new one's

Zinc (long term activation, not from cascade)
Caffeine (hot damn)
(Possibly- manganese)....think pineapple

One other note: adrenalin makes hormone receptors more sensitive, guess the body builders already know this. I think NBE stacking makes sense though, as an example, say immediately after a fitness routine, NBE supplementation should commence, Imo it would follow: (when blood flow and heart rate are peak)

Pre-workout: Take anti-androgen

Post work out: MSM, E2/Phytoestrogens, pro-aromatase, calcium, ATP (astaxanthin), a few slices of pineapple, hydration, I might be missing some, feel free to add to the post work out routine.

As listed, second messengers improve the biosynthesis of hormones, so does ATP (Adenosine triphosphate, and Astaxanthin works quite well for this ), G protein-coupled estrogen receptors (GPER), activation of GPER comes from estrogen, which is the result of adenylyl cyclase and cAMP-dependent signaling.

Cell signaling
http://users.rcn.com/jkimball.ma.ultrane...Messengers

Imo, second messengers are an aromatase for cell bio-synthesis. In other words, first messengers are about cell diffusion, while second messengers boost the intercellular action for DNA syntheses (or cell reaction).

Forskolin is supplement example of a second messenger. Calcium is a second messenger too, and underestimated for NBE. Btw, boosting vitamin D and calcium upregulates ovarian aromatase.

Second messengers are intracellular signaling molecules released by the cell to trigger physiological changes such as proliferation, differentiation, migration, survival, and apoptosis. Secondary messengers are therefore one of the initiating components of intracellular signal transduction cascades. Examples of second messenger molecules include cyclic AMP, cyclic GMP, inositol trisphosphate, diacylglycerol, and calcium. The cell releases second messenger molecules in response to exposure to extracellular signaling molecules—the first messengers. First messengers are extracellular factors, often hormones or neurotransmitters, such as epinephrine, growth hormone, and serotonin. Because peptide hormones and neurotransmitters typically are biochemically hydrophilic molecules, these first messengers may not physically cross the phospholipid bilayer cell membrane to initiate changes within the cell directly—unlike steroid hormones, which usually do. This functional limitation necessitates the cell to devise signal transduction mechanisms to transduce first messenger into second messengers, so that the extracellular signal may be propagated intracellularly. An important feature of the second messenger signaling system is that second messengers may be coupled downstream to multi-cyclic kinase cascades to greatly amplify the strength of the original first messenger signal.[1][2] For example, Ras.GTP signals link with the Mitogen Activated Protein Kinase (MAPK) cascade to amplify the allosteric activation of proliferative transcription factors such as Myc and CREB. (Wiki) https://en.m.wikipedia.org/wiki/Second_messenger_system

Interesting in that calcium supplementation is suggested when taking PM, I wonder if they new that calcium improves cell biosynthesis, or was it from PM lowering the parathyroid?, hmmmm.

Anyways, The daily recommended is 1000 mg to 1200 mg, although topping out at 2500 mg, certain restrictions (interactions) need to be observed though, (check with your doctor) e.g calcium channel blockers. Carbs increase the absorption of calcium while coffee decreases it (MF'er)

Here is some excellent info on second messengers:

Second Messenger
http://users.rcn.com/jkimball.ma.ultrane...ml#IP3_DAG

Bottom line, here's one example of thinking inside the box (the cell) lol makes sense. Meaning looking at cell diffusion and how boosting the calcium signal (via calcium ion channels) improves the DNA synthesis of NBE/Hrt, just my opinion on that part though.

Calcium
http://umm.edu/health/medical/altmed/supplement/calcium

[tanysquirrel]

lol..i knew I could count on you to make sense of it

what Yoda is to starwars you are to NBE/Breast Nexus

Follow pathways you must,Grow boobies, you will

[Lotus]

lol..i knew I could count on you to make sense of it

what Yoda is to starwars you are to NBE/Breast Nexus

Follow pathways you must,Grow boobies, you will

You funny girl, keep on finding these acorns, I like reading them. Though you might find that BN archives hold a treasure trove of NBE nifty nuggets.

Good luck

[tanysquirrel]

lol..i knew I could count on you to make sense of it

what Yoda is to starwars you are to NBE/Breast Nexus

Follow pathways you must,Grow boobies, you will

You funny girl, keep on finding these acorns, I like reading them. Though you might find that BN archives hold a treasure trove of NBE nifty nuggets.

Good luck

oh wise and Venerable Booby-Jedi Master, I do concur with the nuggets of info buried deep in the archives, to which I see the infamous "admin" dredges up from time to time I crawl through the internet searching the maze of cross-linked info for future use? perhaps I should look deep in the catacombs of the archives for the dusty tomes of wisdom, and search from there ..just hope my dust allergies don't act up Idiana Jones Squirrel.. bah baaah bah baaah, bah ba baaah (Indiana jones theme)..