26-04-2014, 08:56 PM
In an abstract I read, it suggests that soy CAUSES an increased rate of breast tumor growth and inhibits an anti-tumor antagonist called tamoxifen:
http://www.ncbi.nlm.nih.gov/pubmed/11573864
Unfortunately I'm not able to read the full article, but it comes to that conclusion despite stating that at "high concentrations" (whatever that means) it has an opposite effect. From the abstract it also doesn't say whether the animals were male or female (i.e. already had elevated levels of estrogen).
Perhaps the general rule holds true that the more estrogen receptors activated, the higher risk of breast cancer-- at low concentrations the phytoestrogens can somehow fill in the gaps of other estrogen receptors while at higher concentrations (if in females) breast cancer rates are reduced since the weaker phytoestrogens compete with the much stronger natural E2s. Just my best guess.
I read from another random site:
http://www.drweil.com/drw/u/QAA401156/Ho...s-Soy.html
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Breast cancer: Theoretically, the phytoestrogens in soy can attach to estrogen receptors and block the effect of estrogen, the hormone most types of breast cancer cells need in order to multiply. If so, consuming soy foods could reduce the risk of breast cancer, but study results have been conflicting: some show that soy consumption lowers the risk of breast cancer while others have found no such evidence; some studies have even suggested that concentrated supplements of soy proteins may stimulate the growth of breast cancer cells. Results of a big study from Shanghai published in 2009 found that women participants whose intake of soy protein was highest when they were teenagers or young adults had a risk of pre-menopausal breast cancer that was 60 percent lower than participants whose soy protein intake during those young years was lowest. As far as other types of cancer are concerned, no good evidence demonstrates that substances in soy foods are protective against
endometrial, ovarian, colorectal, prostate and other cancers.
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Weaker estrogens replacing stronger estrogens can explain why female Asian populations that consume lots of soy products have low rates of breast cancer. What I would like to know is if anyone equivalently studied the male Asian population for breast cancer. From my gut-feeling, I think it will be hard to imagine that a bio male with as many estrogen receptors activated as a bio woman will not have an elevated risk of breast cancer compared to their regular low E male selves.
Overall, I think eating soy (at least non-GMO) moderately will have more benefits than harm, looking at all the vitamins it has. This link from cancer.org also provides the bottom line.
http://www.cancer.org/cancer/news/expert...-risk.aspx
Does anyone have any thoughts?
http://www.ncbi.nlm.nih.gov/pubmed/11573864
Unfortunately I'm not able to read the full article, but it comes to that conclusion despite stating that at "high concentrations" (whatever that means) it has an opposite effect. From the abstract it also doesn't say whether the animals were male or female (i.e. already had elevated levels of estrogen).
Perhaps the general rule holds true that the more estrogen receptors activated, the higher risk of breast cancer-- at low concentrations the phytoestrogens can somehow fill in the gaps of other estrogen receptors while at higher concentrations (if in females) breast cancer rates are reduced since the weaker phytoestrogens compete with the much stronger natural E2s. Just my best guess.
I read from another random site:
http://www.drweil.com/drw/u/QAA401156/Ho...s-Soy.html
-----
Breast cancer: Theoretically, the phytoestrogens in soy can attach to estrogen receptors and block the effect of estrogen, the hormone most types of breast cancer cells need in order to multiply. If so, consuming soy foods could reduce the risk of breast cancer, but study results have been conflicting: some show that soy consumption lowers the risk of breast cancer while others have found no such evidence; some studies have even suggested that concentrated supplements of soy proteins may stimulate the growth of breast cancer cells. Results of a big study from Shanghai published in 2009 found that women participants whose intake of soy protein was highest when they were teenagers or young adults had a risk of pre-menopausal breast cancer that was 60 percent lower than participants whose soy protein intake during those young years was lowest. As far as other types of cancer are concerned, no good evidence demonstrates that substances in soy foods are protective against
endometrial, ovarian, colorectal, prostate and other cancers.
-----
Weaker estrogens replacing stronger estrogens can explain why female Asian populations that consume lots of soy products have low rates of breast cancer. What I would like to know is if anyone equivalently studied the male Asian population for breast cancer. From my gut-feeling, I think it will be hard to imagine that a bio male with as many estrogen receptors activated as a bio woman will not have an elevated risk of breast cancer compared to their regular low E male selves.
Overall, I think eating soy (at least non-GMO) moderately will have more benefits than harm, looking at all the vitamins it has. This link from cancer.org also provides the bottom line.
http://www.cancer.org/cancer/news/expert...-risk.aspx
Does anyone have any thoughts?