(¯`’·¸¸Born This Way¸¸.·”´¯)
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(10-09-2014, 01:04 PM)Jaded Jade Wrote: It might be nice to start a "Born This Way" thread with science and studies partially for interesting reading, but also to have an archive of references to enlighten others.
- JJ
So here is a collection of links about physical and mental differences in Male to Female Transsexuals.
These links are not meant for self diagnosis because transsexualism is extremely complicated and a huge amount of research still needs to be done.
Androgen Receptor Repeat Length Polymorphism Associated with Male-to-Female Transsexualism.
Human Molecular Genetics Laboratory, Prince Henry's Institute of Medical Research, Melbourne, Australia.
Quote:A significant association was identified between transsexualism and the AR allele, with transsexuals having longer AR repeat lengths than non-transsexual male control subjects (p = .04)
Quote:This study provides evidence that male gender identity might be partly mediated through the androgen receptor.
Regional gray matter variation in male-to-female transsexualism.
Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095-7334, USA.
Quote:MTF transsexuals show a significantly larger volume of regional gray matter in the right putamen compared to men. These findings provide new evidence that transsexualism is associated with distinct cerebral pattern, which supports the assumption that brain anatomy plays a role in gender identity.
Sex differences in verbal fluency during adolescence: a functional magnetic resonance imaging study in gender dysphoric and control boys and girls.
VU University Medical Center, Amsterdam, the Netherlands
Quote:The better performance of MtFs is consistent with our expectation that MtFs perform better on female-favoring tasks. Moreover, they produced more words than girls and FtMs. Even though a trendwise linear increase in brain activity between the four groups only approached significance, it may indicate differences in individuals with gender identity disorder compared to their birth sex.
Sexual differentiation of the brain and behavior.
Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA Amsterdam ZO, The Netherlands
Quote:During the intrauterine period the human brain develops in the male direction via direct action of a boy's testosterone, and in the female direction through the absence of this hormone in a girl. During this time, gender identity (the feeling of being a man or a woman), sexual orientation, and other behaviors are programmed. As sexual differentiation of the genitals takes places in the first 2 months of pregnancy, and sexual differentiation of the brain starts during the second half of pregnancy, these two processes may be influenced independently of each other, resulting in transsexuality. This also means that in the case of an ambiguous gender at birth, the degree of masculinization of the genitals may not reflect the same degree of masculinization of the brain. Differences in brain structures and brain functions have been found that are related to sexual orientation and gender.
The microstructure of white matter in male to female transsexuals before cross-sex hormonal treatment. A DTI study.
Departamento de Psicobiología, UNED, C/ Juan del Rosal 10, 28040 Madrid, Spain
Quote:Our results show that the white matter microstructure pattern in untreated MtF transsexuals falls halfway between the pattern of male and female controls. The nature of these differences suggests that some fasciculi do not complete the masculinization process in MtF transsexuals during brain development.
Finger Length Ratios in Serbian Transsexuals.
Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Dr Subotića 13, 11000 Belgrade, Serbia
Quote:Transsexualism in humans is biological in origin. Our findings support a biological etiology of MFT implicating decreased prenatal androgen exposure in MFT. 2D : 4D could be potentially used as a marker for prenatal androgen exposure.
I will post more as and when I find it.
Please feel free to add your own findings.
Denita
I constantly have to look up and cross check stuff. I will try to put a conclusion up for each so there no need to read the whole paper unless you want too.
