[Lotus]

Dr. Duke's
Phytochemical and Ethnobotanical Databases


Chemicals with Estrogenic Activity

ALLOIMPERATORIN
ALOE-EMODIN
ANETHOLE
APIGENIN 16% genistein EC50=0.1-25 uM/l EC50=1 uM
AURANTIOBTUSIN
BETA-SITOSTEROL
BIOCHANIN-A 0.1 uM EC50=0.1-25 uM/l
BORON 3 mg/man/day
BUTIN
CHRYSIN
CITRAL
COUMARIN
COUMESTROL
DAIDZEIN EC50=0.1-25 uM/l
DAIDZIN
DESERPIDINE
DIANETHOLE
DIOSGENIN 20-40 mg/kg/day/15 day scu mus
DIOSMETIN EC50=2.9 uM
EMBELIN
EMODIN
ESTRADIOL
ESTRIOL 500 ug/day/orl/wmn
ESTRONE 0.1-5 mg/woman/day
FLAVONE
FORMONONETIN
GENISTEIN EC50=0.1-25 uM/l
GENISTIN
GERANIAL
GLABRIDIN
GLYCITEIN
GLYCYRRHIZIN
INDOLE-3-CARBINOL
IRIFLOPHENONE
IRILONE
IRISOLONE
ISOLIQUIRITIGENIN
ISOXANTHOHUMOL
KAEMPFEROL EC50=0.1-25 uM/l EC50=0.56 uM
LAPACHOL
LICOCHALCONE-A
LUTEOLIN 58% genistein
NARINGENIN EC50=0.1-25 uM/l
NEROL
PHLORETIN EC50=0.1-25 uM/l
PUERARIN
QUERCETIN 10% genistein
RESVERATROL 22% of genistein
RHAPONTICIN
STIGMASTEROL
TRICIN
WOGONIN 10 mg/kg/day
XANTHOHUMOL

Tue Feb 24 21:18:42 EST 2015

Please send questions and comments to:
James A. Duke
Green Farmacy Garden
8210 Murphy Road
Fulton, MD 20759

or Mary Jo Bogenschutz (E-Mail: godwinm001@hawaii.rr.com)
Dr. Duke does not recommend self diagnosis or self medication. Please see the disclaimer for more information.

[ellacraig]

So definitely no more coffee?

[Lotus]

So definitely no more coffee?

Simple answer?, yes.

The chemicals speak for themselves, but yeah, I'll spare the techno stuff.

[ellacraig]

Being realistic... Are these chemicals limited to only "caffeine"?
Like would some of them be present in DECAF as well? I mean they are only extracting the caffeine outta the beans right... So shud all form of coffee be avoided?

[ellacraig]

Being a b cup by rights is probably realistic for my body type. I'm tall and slim BUT all the women in my family don't drink coffee AND have bigger body types and boobs
Maybe I quit coffee and I become what I'm genetically predisposed to... Interesting concept

[Lotus]

Being realistic... Are these chemicals limited to only "caffeine"?
Like would some of them be present in DECAF as well? I mean they are only extracting the caffeine outta the beans right... So shud all form of coffee be avoided?

Coffee is a love hate relationship, I've seen info on decaf and there is some caffeine left in decaf. For me I'll stop drinking coffee for a bit and then say screw it, I need my coffee. Besides, I see about 15-16 chemicals in coffee benefiting NBE, makes feel more secure about it even if the amounts are small, I'll take it.

[The First Aria]

I really cant tell you how much coffee I drink a day. And since I was diagnosed with Gyne and actually trying to "help" nature out a bit. LOL... I went from "girlie nubs" to now wearing a lot of 38C's and some D's. in about 3 and 1/2 years.

So, not to be butting heads intentionally with the "Boobologist" like Lotus..... I say, that's when you stopped preaching and started to mettleling. LOL

[ellacraig]

I really cant tell you how much coffee I drink a day. And since I was diagnosed with Gyne and actually trying to "help" nature out a bit. LOL... I went from "girlie nubs" to now wearing a lot of 38C's and some D's. in about 3 and 1/2 years.

So, not to be butting heads intentionally with the "Boobologist" like Lotus..... I say, that's when you stopped preaching and started to mettleling. LOL

Lucky prick lol

[myboobs]

Well I haven't posted a pic for sometime now, so here goes, I ve nbeen does the healthy fat plan, ben helping other people too. good night. A new plan with be posted soon.

Most immpresive queen of boobies
What are your under and across measurements ?

[spanky (aka Lola)]

Well the dosage part I'm not sure about yet, but if we go by binding affinity this applies:

High-affinity ligand binding implies that a relatively low concentration of a ligand is adequate to maximally occupy a ligand-binding site and trigger a physiological response.

Binding affinity data alone does not determine the overall potency of a drug. Potency is a result of the complex interplay of both the binding affinity and the ligand efficacy. Ligand efficacy refers to the ability of the ligand to produce a biological response upon binding to the target receptor and the quantitative magnitude of this response. This response may be as an agonist, antagonist, or inverse agonist, depending on the physiological response produced.[8]

http://wikipedia.org/wiki/Ligand_(biochemistry)

But the amount (dosage) will be be different in men and women, some of the recommendations say low dose in men counters prolactin release, while higher dosages inhibit it.

Take for instance this study:

Vitex agnus-castus extracts for female reproductive disorders: a systematic review of clinical trials.

In premenstrual dysphoric disorder, one study reported Vitex to be equivalent to fluoxetine, while in the other, fluoxetine outperformed Vitex. In latent hyperprolactinaemia, one trial reported it to be superior to placebo for reducing TRH-stimulated prolactin secretion, normalising a shortened luteal phase, increasing mid-luteal progesterone and 17β-oestradiol levels, while the other found Vitex comparable to bromocriptine for reducing serum prolactin levels and ameliorating cyclic mastalgia.
http://www.ncbi.nlm.nih.gov/pubmed/23136064

So we really need to be careful with recommendations. But, I still want more info on vitex, but it "is" a phytoestrongen.

The concerns about vitex centers around how it influences dopamine, but I think this can (vitex) goes deeper than that, I believe it also plays a big part in lipid oxidation, which is huge because that ties into anti-inflammtories, free radical scavengers, degenerative conditions and of course Eicosanoid Pathway, which involves COX inhibitors (big time aromatase).

You know the view or shoud I say the research over the last decade or two has shown that fatty acids are a preventive measure against cancer. So, there's plenty of debate for sure, I certainly won't try to change someone's mind about it, I'll just refer them to research, like I did, I was completely against increased intake of FFA's, and I was in the industry for 30 years.

I will say this, if you don't have fitness in a NBE plan and take this approach you'd better be prepared to get chunky, cause fat loves making more fat.

Lotus - I really appreciate all of the information you provide. I try to do my own looking around, although I do not have the knowledge base that you and some others have, so I have trouble interpreting much of what I read. I would like to try vitex and maybe palmitic acid, but just want to know a little more about any associated risks first.