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confused

#11

Somewhere in DNA (the genome) influences its direction, why!, what tells testosterone to synthesize to DHT?. How long is this synthesis?.

With some nbe/hrt products they only partially (attach) to cell surfaces and does nothing, (much like being hit with a paintball lol) we want what can cross into the nucleus and cause transcription to the mitochondria, that's what causes cells to grow (in layperson, if you will), sorry, best i got atm. Rolleyes

Ok, so the battle upstream is waged with 5 alpha reductase inhibitors and pro-aromatase (not impressively right?). So then, elimination is the key because of the metabolite 3 beta diol, which oh by the way resides in the testes (only half the story). The other half is in the prostate, which I might add has the potential of almost pure estrogen (by the same metabolite). Elimination of DHT in the testes, synthesize 3 beta diol in the prostrate, and this is where I stop, not to be a pain mind you, but this is where the true research begins, (which is partly why I step away from BN at the end of the week).......more research. Wink
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#12

Smile Thank you so much for your scientific approach. Getting breasts isn´t actually my main goal but a nice bonus if that happens. I live in Europe so the Estriol creams are freely available in pharmacies. I´ve been using 0,5mg daily for over 2 years and I´ve noticed clear mental effects and some fat redistribution particularly in my face. My face looks much more feminine than 2 years ago. The change is obvious and it´s easily seen in photographs. There´s also more fat on my hips and butt area and my testicles have also noticeably shrunk.
Women use estriol creams intravaginally and a medical study has proven, that 1 dose which is 0,5mg, equals 8-12mg taken orally. The group of women were tested for their serum level of estriol 1-2 hours after using intravaginal estriol cream.
Unfortunately I don´t have a vagina, so my practical solution was to rub a cream directly to my glans and under foreskin where there´s mucous membrane that resembles vaginal surface. Skin is thin and there are lots of blood vessels.

SP is said to interfere the effect of hormones, in my case estriol. That´s why I´d like to find a way to lower my DHT without sacrificing the feminizing effect of estriol.
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#13

Progesterone blocks DHT production and if you don't have ovaries and are taking estrogen, you likely need more progesterone anyway in order to prevent the effects of estrogen dominance.
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