[The First Aria]

You little bastard...:p the only line I can fill up with botox is the one below my back...but lets not do that:p Ill take a look at the thread, thanks L!

* havent you tried boron btw? I read this: - Helps in production of estrogen. Boron might improve the production of estrogen in menopausal women, bringing back their sex drive within a few days of treatment. Boron increases the level of natural sex hormones in the body, thereby reducing the need for Hormone replacement therapy....something for the guys here?

I'm not too sure, since bio men produce small amounts of estrogen, unless severely over weight. It might help ease the amount needed to do things though?

[Lotus]

Found this interesting chart about how many times pumping is recommended here:
http://www.bodybeauty.co.za/breast.html

If the link doesn't work it says...

A session takes 10min or less and can be taken as follows:

Days after menstrual Cycle Result Times per week

1-7 Strengthening Period Twice

7-17 Breast Enhancing Period Every 2nd day or every day

17-24 Consolidation Period Three times

During menstrual Cycle Not Recommended


Not sure if this has been discussed at all before but thought I'd share.

Thanks for the info spooky,

This is the first time I've seen a recommendation not to pump during menstruation. I think most people develop their own schedule (time permitting). 10 min. sessions are effective from my experience.

Too bad no matching science isn't attached lol, I'd sure like to know more about the breast enhancing period (days 7-17).

Thanks again.

[charrr]

"Oh yeh lol I do the same but Im so bad at hiding it...and everytime I need a supplement I sneak into my ''secret room'' with ''secret closet'' and then I start coughing while opening all kinds off jars and plastic bags where I keep all those treasures..lol. Very obvious too...."

Hahahahaha! I laughed out loud about that!

[Lotus]

"Oh yeh lol I do the same but Im so bad at hiding it...and everytime I need a supplement I sneak into my ''secret room'' with ''secret closet'' and then I start coughing while opening all kinds off jars and plastic bags where I keep all those treasures..lol. Very obvious too...."

Hahahahaha! I laughed out loud about that!

Lmao Hannah @ secret room equipped with secret compartment, classic lol. I see pumping being no stealth mode action either........re: a clank/gong of the dome hitting each other (and for god sakes don't drop em') click of the airlock, and a swoosh/piff-puff or otherwise weird noise coming from the hand pump are dead giveaways for a " hey what the hell you doing in there ". But.......you could jiggle the toilet handle, turn on the hair dryer/music etc and say what?, can't hear yah...........or nunya business.

[Lotus]

I see gonadotropin-releasing hormone (GnRH) as a replacement for anti-androgens, yup!, you won't need them if the pituitary suppresses the release of lutenizng hormone LH, and FSH follicle stimulating hormone. In this case, the use of GnRH antagonists effectively shuts testosterone production in the testes/adrenals off, thus eliminating the need for AA's, this leaves estrogen unopposed, and reducing the need for increased amounts of supplements sparing the endocrine system.

So, we be looking (lol, sending out a bolo) for a plant origin non-peptide orally-active GnRH antagonists, easy huh?.


Unlike the GnRH agonists, which cause an initial stimulation of the hypothalamic-pituitary-gonadal axis (HPGA), leading to a surge in testosterone or estrogen levels, GnRH antagonists have an immediate onset of action, rapidly reducing sex hormone levels without an initial surge.
source:wiki


Progress towards the development of non-peptide orally-active gonadotropin-releasing hormone (GnRH) antagonists: therapeutic implications.
Review article
Millar RP, et al. Br Med Bull. 2000.
Show full citation
Abstract
Gonadotropin-releasing hormone (GnRH) is a decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly.NH2) which is produced from a precursor polypeptide in hypothalamic neurons and secreted in a pulsatile fashion to stimulate the secretion of LH and FSH via its interaction with a cognate receptor on gonadotropes. Low doses of the native peptide delivered in a pulsatile manner to mimic that found in the hypothalamic portal vessels restore fertility in hypogonadal patients, and are also effective in treating cryptorchidism and delayed puberty. Administration of high doses of GnRH, or agonist analogues, causes desensitization of the gonadotrope with consequent decline in gonadal gametogenesis and steroid and peptide hormone synthesis. This phenomenon finds extensive therapeutic application in clinical medicine in a wide spectrum of disease (Table 1). In addition, GnRH analogues have promise as new generation male and female contraceptives in conjunction with steroid hormone replacement. GnRH antagonists inhibit the reproductive system through competition with endogenous GnRH for the receptor and, in view of their rapid effects, are being increasingly used for the above mentioned applications. The peptide agonists and antagonists currently available require parenteral administration, typically in the form of long-acting depots. A new generation of non-peptide GnRH antagonists are beginning to emerge which should allow oral administration and, therefore, may provide greater flexibility of dosing, lower costs and increased patient acceptance.

[Lotus]

An androgen antagonist (anti-androgen) can broadly be defined as any compound that has the biological effect of blocking or suppressing the action of male sex hormones such as testosterone within the human body. DHT blocks the conversion of aromatase (bad for breast growth).
____________________________________________________________________

Reishi-reishi mushrooms significantly reduced levels of 5-alpha reductase, preventing conversion of testosterone into the more potent DHT. High levels of DHT are a risk factor for conditions such as benign prostatatic hypertrophy (BPH), acne, and baldness.

White Peony--Estrogenic, blocks 5ar and pro-aromatase - Strong.
A compound found in white peony inhibits the production of testosterone and promotes the activity of aromatase, which converts testosterone into estrogen.

Spearmint-anti-androgenic properties reduce the level of free testosterone in the blood, while leaving total testosterone and DHEAS unaffected.


Green Tea Epigallocatechin-Green tea (camellia)-Reduce's the conversion of free testosterone into DHT and also raises SHBG (sex-hormone-binding-globulin).


Pygeum-include phytosterols that inhibit the production of dht. Pygeum also reduce's prolacting levels and block the accumulation of cholesterol in the prostate. Prolactin increase's the uptake of testosterone by the prostate. Pygeum reduces the levels of DHT in the blood and reduces the number of sites where the dht can attach.


Saw palmetto-Saw palmetto-Beta-sitosterol is a natural alpha-adrenergic receptor blocker. Prevents DHT from accumulating in prostate tissue that would otherwise cause excessive cell growth and inflammation. The plant steroids in saw palmetto also act on progesterone receptors, an action that causes a reduction in estrogen levels.


DIM is Diindolylmethane-It is an anti carcinogen and also improves estrogen metabolism. Plant-derived 3,3′-Diindolylmethane Is a Strong Androgen Antagonist in Human Prostate Cancer Cells* DIM is remarkably similar in conformational geometry and surface charge distribution to an established synthetic AR antagonist, Taken with estrogen agonist, activities of DIM are seen as an hormone disrupter. DIM is the first example of a pure androgen receptor antagonist from plants.


Nettle Root--Binds to SHBG (hormone that binds to excess hormones by decreasing hormone levels), and decreases 5ar and aromatase. Taking this tends to increase estrogen and testosterone. Would need to be taken with a pro-aromatase, and maybe estrogen.


Chinese Skullcap Inhibits the 5alpha-reductase enzyme-
Baicalein has been shown to inhibit the 5alpha-reductase enzyme, which converts testosterone to dihydrotestosterone (DHT). DHT is strongly associated with the development of prostate enlargement (benign prostatic hyperplasia) and prostate cancer. As such, baicalein is reported to be potentially useful for the prevention and/or treatment of androgen-dependent (testosterone-driven) disorders, including prostate enlargement and prostate cancer.


Licorice (Glycyrrhiza glabra)-Anti-androgenic and activates alpha and beta estrogen receptors and blocks 5-ar - Strong, but take in moderation!
Use with extreme caution

-For most disorders: Take 200 mg standardized extract in pill form three times a day, or 20 to 45 drops, three times a day, of a 1:5 tincture. (The 1:5 tincture represents one part herb is soaked in five parts liquid


Pumpkin Seed Oil: Has been demonstrated to inhibit DHT formation through the inhibitory effect on 5-alpha-reductase activity. Pumpkin seed oil breaks down DHT via the liver.


Emu Oil: Research has shown that emu oil contains a high level of linolenic acid which further research has shown to be an efficient antiandrogen. Linolenic acid is a potent 5 alpha reductase inhibitor and may be usefull in the treatment of disorders related to the hormone Dihydrotestosterone. Linolenic Acid has been suggested to be of use in the disorders such as benign prostratic hyperplasma, acne androgenetic alopecia and hirsuitism.


Even though it's not an AA it's worth mentioning because of its interaction.

L-Lysine: While L-Lysine is NOT a DHT blocker, it may make DHT blockers more effective. Researchers have found that adding a supplementation of L-Lysine can make drugs like Propecia more effective. Since propecia is a DHT inhibitor, as all the natural products mentioned here, the addition of a L-Lysine supplement can make these products also more effective. Studies has shown that L-Lysine combined with a DHT inhibitor can for example promote hair growth in people suffering from androgenetic alopecia.


Considering the potential to block DHT and increase aromatase adding fatty acids makes sense, only don't forget a fitness plan.

Anti-androgenic activity of fatty acids.

In this study, we show that 5alpha-reductase derived from rat fresh liver was inhibited by certain aliphatic free fatty acids. The influences of chain length, unsaturation, oxidation, and esterification on the potency to inhibit 5alpha-reductase activity were studied. Among the fatty acids we tested, inhibitory saturated fatty acids had C12-C16 chains, and the presence of a C==C bond enhanced the inhibitory activity. Esterification and hydroxy compounds were totally inactive. Finally, we tested the prostate cancer cell proliferation effect of free fatty acids. In keeping with the results of the 5alpha-reductase assay, saturated fatty acids with a C12 chain (lauric acid) and unsaturated fatty acids (oleic acid and alpha-linolenic acid) showed a proliferation inhibitory effect on lymph-node carcinoma of the prostate (LNCaP) cells. At the same time, the testosterone-induced prostate-specific antigen (PSA) mRNA expression was down-regulated. These results suggested that fatty acids with 5alpha-reductase inhibitory activity block the conversion of testosterone to 5alpha-dihydrotestosterone (DHT) and then inhibit the proliferation of prostate cancer cells.
http://www.ncbi.nlm.nih.gov/pubmed/19353546

Evening Primrose Oil- massage, Fibrocystic breast pain, treats hot flashes, relieves PMS symptoms, relieves Eczema, hormone balance, fights breast tumors and diabetes. Reports have GLA-Gamma-Linolenic Acid as helping with RA and arthritis, diabetic neuropathy, ADHD and CFS (chronic fatigue syndrome). And UPDATED to include it being an inhibitor of 5 alpha-reductase, the enzyme that converts testosterone to DHT, (DHT is bad for BOOB GROWTH).

Coconut Oil- Makes connective tissues stronger, superb antioxidant, neutralizes free radicals and slowing down aging, aids in breast feeding, nature's richest source of MCFAs. 5 ar inhibitor, aromatase



________________________________________

Reishi (Ganoderma lucidum)
Red reishi, commonly known as LingZhi in Chinese, is a mushroom thought to have many health benefits. In a research study exploring the anti-androgenic effects of 20 species of mushrooms, reishi mushrooms had the strongest action in inhibiting testosterone (3). That study found that reishi mushrooms significantly reduced levels of 5-alpha reductase, preventing conversion of testosterone into the more potent DHT. High levels of DHT are a risk factor for conditions such as benign prostatatic hypertrophy (BPH), acne, and baldness.

White Peony (Paeonia lactiflora)
Chinese peony is a widely grown ornamental plant with several hundred selected cultivars. Many of the cultivars have double flowers with the stamens modified into additional petals. White peony has been important in traditional Chinese medicine and has been shown to affect human androgen levels in vitro. In a 1991 study in the American Journal of Chinese Medicine Takeuchi et al described the effects of paeoniflorin, a compound found in white peony that inhibited the production of testosterone and promoted the activity of aromatase, which converts testosterone into estrogen (7). To date, there have been no studies that translate or explore the clinical effects.

Chaste Tree (Vitex agnus-castus)
Chaste tree (or chasteberry) is a native of the Mediterranean region and is traditionally used to correct hormone imbalances. In ancient times, it was believed to be an anaphrodisiac, hence the name chaste tree. Clinical studies have demonstrated effectiveness of medications produced from extract of the plant in the management of premenstrual syndrome (PMS) and cyclical mastalgia (14). The mechanism of action is presumed to be via dopaminergic effects resulting in changes of prolactin secretion from the anterior pituitary. At low doses, it blocks the activation of D2 receptors in the brain by competitive binding, causing a slight increase in prolactin release. In higher concentrations, the binding activity is sufficient to reduce the release of prolactin (15).

Reduction in prolactin levels affects FSH and estrogen levels in females and testosterone levels in men. There is as yet no information regarding its efficacy in endocrine disease states such as PCOS, however, one small-scale study has demonstrated this prolactin reducing effect in a group of healthy males, and the implication is that it could be of use in mild hyperprolactinemia (16, 17). One could also theorize that it could be refined for use as a male contraceptive, because testosterone reduction should reduce libido and sperm production. This topic is further explored in a review by Grant & Anawalt (18).



http://www.ncbi.nlm.nih.gov/pmc/articles...10-497.pdf

http://endometabol.com/?page=article&article_id=3644

[Lotus]

Btw,

Lauric acid (C-12 fatty acid) inhibits 5 alpha reductase type 1 & 2......meaning it inhibits DHT, no other supplement that I know inhibits type 1 & 2 , 5 alpha reduces. Pharma dutaseride does this too.

Lauric acid is present in coconut oil (medium chained fatty acid), which is readily active (orally) in the blood stream, via the portal vein.

[Lotus]

Hi all,

Here's some info I've put together on enhancing breasts (mostly skin application).


Stimulating lipid synthesis increases the volume of adipocytes (fatty tissues found in breasts). Avocado oil, emu oil are excellent carrier oils. Palmitoyl (Pentapeptide) aka -peptides, (see below), Caprylic/Capric Triglyceride, Dictyopteris Oil, are important for cellular binding and lipid synthesis. Macadamia nut oil stimulates estrogen receptor alpha (ER-a).

[i]Fatty Acid and Lipid Synthesis
http://dwb4.unl.edu/Chem/CHEM869P/CHEM86...idSyn.html

Adipose Tissue: Not Just Fat
http://themedicalbiochemistrypage.org/ad...tissue.php

Acute in vitro production of acylation stimulating protein in differentiated human adipocytes
http://www.jlr.org/content/38/1/1.full.pdf

The three features of skin penetration enhancer activity (Lipid interaction, Protein alteration and Partitioning phenomena) represent the essential aspects of the LPP theory.

Lipid-protein-partitioning (LPP) theory of skin enhancer activity: finite dose technique
http://www.sciencedirect.com/science/art...7389902603

Cell Penetrating Peptides
http://wikipedia.org/wiki/Cell-penetrating_peptide

[pom19]

Btw,

Lauric acid (C-12 fatty acid) inhibits 5 alpha reductase type 1 & 2......meaning it inhibits DHT, no other supplement that I know inhibits type 1 & 2 , 5 alpha reduces. Pharma dutaseride does this too.

Lauric acid is present in coconut oil (medium chained fatty acid), which is readily active (orally) in the blood stream, via the portal vein.

-----------------------------------------------------------------------
This morning my wife asked me if I like coconut oil (Organic Virgin) in my coffee (she loves it in hers.) and I said yes with hesitation (I like my coffee black). But after adding it the color of my coffee did not change which I was very happy about.
Now you say it has Lauric acid. Thanks as usual Lotus.

[Lotus]

Btw,

Lauric acid (C-12 fatty acid) inhibits 5 alpha reductase type 1 & 2......meaning it inhibits DHT, no other supplement that I know inhibits type 1 & 2 , 5 alpha reduces. Pharma dutaseride does this too.

Lauric acid is present in coconut oil (medium chained fatty acid), which is readily active (orally) in the blood stream, via the portal vein.

-----------------------------------------------------------------------
This morning my wife asked me if I like coconut oil (Organic Virgin) in my coffee (she loves it in hers.) and I said yes with hesitation (I like my coffee black). But after adding it the color of my coffee did not change which I was very happy about.
Now you say it has Lauric acid. Thanks as usual Lotus.

Lol, that's gotta be better (healthier) than the partially hydrogenated oils (corn oil) in non-dairy creamers.

Cool, thanks Pom.