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Project X (hrt)

(11-04-2016, 05:01 AM)Lotus Wrote:  
(11-04-2016, 04:55 AM)pom19 Wrote:  
(11-04-2016, 04:28 AM)Lotus Wrote:  Btw,

Lauric acid (C-12 fatty acid) inhibits 5 alpha reductase type 1 & 2......meaning it inhibits DHT, no other supplement that I know inhibits type 1 & 2 , 5 alpha reduces. Pharma dutaseride does this too.

Lauric acid is present in coconut oil (medium chained fatty acid), which is readily active (orally) in the blood stream, via the portal vein.
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This morning my wife asked me if I like coconut oil (Organic Virgin) in my coffee (she loves it in hers.) and I said yes with hesitation (I like my coffee black). But after adding it the color of my coffee did not change which I was very happy about.
Now you say it has Lauric acid. Thanks as usual Lotus. Smile


Lol, that's gotta be better (healthier) than the partially hydrogenated oils (corn oil) in non-dairy creamers.

Cool, thanks Pom. Wink
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Absolutely-Smile
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There's an alternative for supplementing coconut oil for those who've had trouble taking CO, it's called Caprylic Acid, (MCFA too), it also has an added benefit of inhibiting ghrelin, the hunger (go switch lol) hormones that promotes obesity.


The attached study outlining increased GH in obesity.........I'm thinking if Moobs are a result of obesity in men, what are the chances that increased GH in the presence of E2 will be the go button for additional (female type) boob growth.


Marked GH secretion after ghrelin alone or combined with GH-releasing hormone (GHRH) in obese patients.
Alvarez-Castro P, et al. Clin Endocrinol (Oxf). 2004.
Show full citation
Abstract
OBJECTIVES: Ghrelin is a 28-amino-acid peptide, predominantly produced by the stomach. It displays a strong GH-releasing activity mediated by the hypothalamus-pituitary GH secretagogue (GHS)-receptor (GHS-R). There are different studies that suggest the importance of ghrelin in feeding and weight homeostasis. In obesity there is a markedly decreased GH secretion. For both children and adults, the greater the body mass index (BMI), the lower the GH response to provocative stimuli, including the response to GHRH. However, the response to the natural GH secretaogogue ghrelin is unclear at the present time. The aim of the present study was to evaluate the GH response to ghrelin alone or combined with GHRH in a group of obese patients, in order to further understand the deranged GH secretory mechanisms in obesity and to clarify the mechanism of action of ghrelin.

PATIENTS AND MEASUREMENTS: Six obese female patients (31 +/- 3.4 years) with a BMI of 36.1 +/- 7.7 kg/m(2) were studied. As a control group, six normal nonobese female subjects of similar age and sex were studied. Four tests were performed: placebo, GHRH [1 micro g/kg, no more than 100 micro g, intravenous (i.v.)], ghrelin (1 micro g/kg, no more than 100 micro g, i.v.) and GHRH (1 micro g/kg, no more than 100 micro g, i.v.) plus ghrelin (1 micro g/kg, no more than 100 micro g, i.v.). Blood samples were taken at appropriate intervals for determination of GH. Statistical analyses were performed by Wilcoxon and by Mann-Whitney tests.

RESULTS: After GHRH, the median peak GH secretion in obese patients was 2.4 micro g/l (range 0.9-8.9 micro g/l). Ghrelin-induced GH secretion showed in obese patients a median peak of 24.4 micro g/l (range 7.4-85.0 micro g/l), significantly greater than the response after GHRH (P < 0.05). After the combined administration of GHRH plus ghrelin in obese patients the median peak GH secretion was 39.9 micro g/l (range 19.2-120.0 micro g/l), significantly greater than the response after GHRH (P < 0.05) or ghrelin (P < 0.05). GHRH-induced GH secretion in normal control subjects showed a median peak of 25.0 micro g/l (range 16.5-33.4 micro g/l). Ghrelin-induced GH secretion in normal showed a median peak of 68.5 micro g/l (range 22.5-119.5 micro g/l), significantly greater than the response after GHRH (P < 0.05). After the combined administration of GHRH plus ghrelin, in normal subjects the median peak GH secretion was 117.8 micro g/l (range 77.5-280.1 micro g/l), significantly greater than the response after GHRH or ghrelin alone (P < 0.05). When we compare the response of normal and obese patients, after GHRH alone, it was markedly decreased in obese people when compared with normal patients (P < 0.05) with a median GH peak of 25.0 micro g/l (range 16.5-33.4 micro g/l) and 2.4 micro g/l (range 0.9-8.9 micro g/l) for normal and obese patients, respectively. When we compare the response of normal and obese patients, after ghrelin alone or GHRH plus ghrelin, it was only blunted in obese subjects when compared with normal subjects with a median GH peak of 68.5 micro g/l (range 22.5-119.5 micro g/l) and 24.4 micro g/l (range 7.4-85 micro g/l) for normal and obese subjects, respectively, after ghrelin alone (P < 0.05) and a median GH peak of 117.8 micro g/l (range 77.5-280.1 micro g/l) and 39.9 micro g/l (range 19.2-120.0 micro g/l) for normal and obese patients, respectively, after GHRH plus ghrelin (P < 0.05).

CONCLUSIONS: This study has demonstrated a massive GH response to ghrelin alone or combined with GHRH in obese patients, suggesting that altered ghrelin secretion could play a major role in the blunted GH secretion present in obese patients.

PMID 15272922 [PubMed - indexed for MEDLINE]
Full text
Full text at journal site
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Fatty acids also promote aromatase, e.g. coconut oil, EPO, borage oil.
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I had stopped taking the Coconut oil due to the high calorie count. I was losing weight by calorie counting which has done wonders. Now I think I need to tone things up. Guess I can add the coconut oil back to my daily rutine.

Thanks for the information, and reminder Lotus!! Smile
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(11-04-2016, 05:43 AM)Fire And Ice Wrote:  I had stopped taking the Coconut oil due to the high calorie count. I was losing weight by calorie counting which has done wonders. Now I think I need to tone things up. Guess I can add the coconut oil back to my daily rutine.

Thanks for the information, and reminder Lotus!! Smile

Hey there Fire,

That's a risk of CO fo sure lol, look into that caprylic acid, swansons has a brand I use 600 mg @ 60 capsules.

I tried a 500 calorie diet for about 7 days and lost 9.75 lbs, whoa!!, talk about extreme, for all its opponents, cal counting works. What I found burned the fat faster then ever before (for me) was changing my ratio of fat/protein/carbs, e.g 10% fat and splitting carbs and protein, (exercise too).
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(11-04-2016, 06:01 AM)Lotus Wrote:  
(11-04-2016, 05:43 AM)Fire And Ice Wrote:  I had stopped taking the Coconut oil due to the high calorie count. I was losing weight by calorie counting which has done wonders. Now I think I need to tone things up. Guess I can add the coconut oil back to my daily rutine.

Thanks for the information, and reminder Lotus!! Smile

Hey there Fire,

That's a risk of CO fo sure lol, look into that caprylic acid, swansons has a brand I use 600 mg @ 60 capsules.

I tried a 500 calorie diet for about 7 days and lost 9.75 lbs, whoa!!, talk about extreme, for all its opponents, cal counting works. What I found burned the fat faster then ever before (for me) was changing my ratio of fat/protein/carbs, e.g 10% fat and splitting carbs and protein, (exercise too).

Yikes, that's a bit extreme. Lowest I've gone is just under 1000 a week, but they say you shouldn't do that. :p I need to start exercising, but I really don't want to. Just me being lazy. As for the coconut oil, I went back and forth researching between pills and raw, I finally went with raw because it was loads cheaper. If I remember correctly I would have to take 10-12 1000 mg pills to equal one table spoon of the oil. So I chose to take it like a shot of tequila, and down the hatch. Wink
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I have mentioned this before, but I think you need to monitor your LDL if you are taking EPO. Mine went up quite significantly when I added both it and coconut oil. I dropped both and my LDL went back to a healthy level, and a cardiologist advised me not to take either. I suspect that the main culprit was EPO, but remain concerned enough that I have resumed neither EPO nor coconut oil.
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Good info, here. I used to take the Dr. Vita CO. It was the best- flavorful, yummy inside and outside the body (beauty aid), and I think it helped my friend with cholesterol issues. Anyway:
There's an alternative for supplementing coconut oil for those who've had trouble taking CO, it's called Caprylic Acid, (MCFA too), it also has an added benefit of inhibiting ghrelin, the hunger (go switch lol) hormones that promotes obesity.

I may also look into this CA, in the future! Not as yummy in banana bread, I assume, but great to have something to help with :
   
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(11-04-2016, 06:01 AM)Lotus Wrote:  Hey there Fire,

That's a risk of CO fo sure lol, look into that caprylic acid, swansons has a brand I use 600 mg @ 60 capsules.

I tried a 500 calorie diet for about 7 days and lost 9.75 lbs, whoa!!, talk about extreme, for all its opponents, cal counting works. What I found burned the fat faster then ever before (for me) was changing my ratio of fat/protein/carbs, e.g 10% fat and splitting carbs and protein, (exercise too).

Here You go. Supports healthy intestinal flora. Said can elicit a strong detox effect which one can only assume means it's doing its job. Strong antifungal. Haven't tried it yet but it's pretty easy to get hold of and cheap.
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Thanks spanky, char, Fire, Ella...great input. Wink

Question-can we eliminate DHT from protein?.

Once DHT reaches fat and muscle tissue it exerts its anabolic effect. Any thoughts on what this (eliminating DHT in protein) would do for NBE?
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