So, I've been absent for some time due to distractions and reality interfering.
I've been on 100 milligrams of spironolactone twice daily for close to ten months now, and recently hit a weight-loss target that my endocrinologist wanted me to beat before starting on full HRT.
As a result I have been using a transdermal estrogen gel for just over a week now, having started on 5/18. 0.75mg of estradiol daily through transdermal application, bypassing the liver entirely. (EstroGel 0.06%)
Three days ago my nipples became insanely tender, the slightest impact feeling like a stab wound. I started with C's due to my weight...but I'm definitely feeling results already, like my bra being slightly tighter.
I almost feel like I'm cheating, skipping three months of waiting for effects...