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How to make PM extract?

#1

I thought about trying to make a extract of PM.

I have a still at home in wich i can make eccential oils or in the case of PM I woul mix the powder with alcohol, let it sit for some time and then run it through the still, to collect an extract of PM at the end. I am just not sure if first of all phytoestrogen is heat resistant (does anyone know? Would be around 80 °C or 175 °F) and if it will evaporate with the alcohol and secondly if it is even soluble in alcohol. 

The other way would be to just put PM in oil or alcohol and let it stand there for a few days, but I think the quality of that is pretty low and the concentration would be much higher if it works with alcohol in the still, since the heat extracts way more then just letting it stand there.

Did anyone here try different ways of extracting the herbs?

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#2

Why?

There is a veritable host of folks here who have gotten consistent results with the pueraria mirifica caps, whole root powder, from what I can see.  You raise the question of whether the active constituents are alcohol soluble, water soluble, fat soluble or a combination of all 3 to obtain results, to say nothing of the constituents' resistance to heat.

If you're wanting to create something for topical application, and don't want to use bio-identical estrogen cream, I'd guess you're the test case.
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#3

The reason is on one side for using since topical has less side effects compared to capsules and the seccond reason is that it also is my hobby to make oils and alcohol. So why not combine my longing for breast with my hobby.

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#4

Oh.  Fair enough.


I see that among other things, the root appears to contain deoxymiroestrol, daidzin, daidzein, genistin, genistein, coumestrol, kwakhurin, mirificine, β-sitosterol, stigmasterol, campesterol, and mirificoumestan. It may also contain cytotoxic compounds.  Only GOD knows what purposes a plant might have for producing substances that are supposedly better for humans than human physiological hormones. You will want to be careful to fully research the properties of each of the known constituents, and understand which ones you will be concentrating, and similarly which ones you may be excluding.  You’d want to have some means for determining how potent you’ve made your resultant extract.  Transdermal delivery becomes another question, as you will need to understand the molecular size of your various extractive elements, and whether or not they can pass the dermal barrier.  Presumably you might even then consider dimethyl sulfoxide as a vehicle to enhance transit.  You might be taking this to a whole new level, but I think you’d need an analytical laboratory to even approach doing it safely.
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#5

Re: The reason is on one side for using since topical has less side effects compared to capsules and the second reason is that it also is my hobby to make oils and alcohol.

That's a new hobby of mine as well (and making rollers as in roll ons).

Having said that, I'm pretty sure Ainterol makes a liquid extract (not just their commonly sold sprays that contain some extract) that you could buy and combine with oils (if you like) rather than attempting to make the same from powders.

Having said that, if you like the topical approach (and personally, I do), their Ainterol Breast Cream is pretty impactful (when used as directed).

Again, I would do a search for the actual extract (it's a liquid) if you intend to mix with oils and alcohol.

Sounds like a fun project! I may have to try that.
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#6

(16-03-2021, 12:31 AM)VergeOfDiscovery Wrote:  Re: The reason is on one side for using since topical has less side effects compared to capsules and the second reason is that it also is my hobby to make oils and alcohol.

That's a new hobby of mine as well (and making rollers as in roll ons).

Having said that, I'm pretty sure Ainterol makes a liquid extract (not just their commonly sold sprays that contain some extract) that you could buy and combine with oils (if you like) rather than attempting to make the same from powders.

Having said that, if you like the topical approach (and personally, I do), their Ainterol Breast Cream is pretty impactful (when used as directed).

Again, I would do a search for the actual extract (it's a liquid) if you intend to mix with oils and alcohol.

Sounds like a fun project! I may have to try that.


Thanks for the info. Maybe if I find their extract, I might even find out how they made it an maybe try that out. Thanks to corona I have to much free time. So any experiment that might even bring interesting or usable results is a great improvement for my day  Big Grin" alt="Big Grin" title="Big Grin">

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#7

I have used Rachaa Pueraria Mirifica Capsules 500mg as the powder for my mix with some success:
https://smile.amazon.com/gp/product/B07BLQ4MXG/


I take the powder out of the pull-apart capsules and grind it up, and mix it with a small amount of CeraVe cream:
https://smile.amazon.com/CeraVe-Moisturi...00TTD9BRC/

I let it sit for at least 5 minutes after mixing to make it combine.


You could use a bulk container of PM to go with the CeraVe and make your own cream pretty inexpensively.


I've found using PM cream on my hips and thighs works well, more so than on the chest. You can also order plastic beauty pants to apply the cream and then fall asleep keeping the cream in place.


PM is more ER-Beta agonist than ER-Alpha agonist. The simplest explanation is that you have more ER-Beta receptors in the lower half of the body, while the breast is primarily ER-Alpha receptors.


I tried using DMSO but it seems to toy with my heart rate and blood pressure more than I would like.

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#8

(16-03-2021, 12:45 AM)Dibraru Wrote:  

(16-03-2021, 12:31 AM)VergeOfDiscovery Wrote:  Re: The reason is on one side for using since topical has less side effects compared to capsules and the second reason is that it also is my hobby to make oils and alcohol.

That's a new hobby of mine as well (and making rollers as in roll ons).

Having said that, I'm pretty sure Ainterol makes a liquid extract (not just their commonly sold sprays that contain some extract) that you could buy and combine with oils (if you like) rather than attempting to make the same from powders.

Having said that, if you like the topical approach (and personally, I do), their Ainterol Breast Cream is pretty impactful (when used as directed).

Again, I would do a search for the actual extract (it's a liquid) if you intend to mix with oils and alcohol.

Sounds like a fun project! I may have to try that.


Thanks for the info. Maybe if I find their extract, I might even find out how they made it an maybe try that out. Thanks to corona I have to much free time. So any experiment that might even bring interesting or usable results is a great improvement for my day  Big Grin" alt="Big Grin" title="Big Grin">



This is what the big jugs of Ainterol Pueraria Mirifica Extract look like: http://naturehut.com/ainterol-pueraria-m...00-.html-1
There are some interesting tips on the necessity to dilute it and percentages for making lotions and creams.

Just found a link for smaller amounts as well: http://naturehut.com/index.php?route=product/category&path=81_84
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#9

I finally found the exact way, even with exact measurements. Just that I don't have the means to make it at home.

For all those who are interested in making PM extract on their own, here is how.


BEST MODES FOR CARRYING OUT THE INVENTION
A better understanding of the present invention may be obtained in light of the following examples which are set forth to illustrate, but are not to be construed to limit the present invention.
EXAMPLE 1 Preparation of Pueraria mirifica Extract
100 g of the tuber of Pueraria mirifica was cleansed, dried at 70 °C for about 5 hours by use of a hot-air drier, and pulverized. To the resulting plant pieces was added 500 mL of a mixture of methanol and water (80/20 v/v), followed by the extraction at 50 °C for about 6 hours. After being filtered, the extract was concentrated in a vacuum to remove the solvent. The concentrate was freeze-dried leaving a brownish solid which was then measured for isoflavone content. Contents of isoflavones in the extract derived from the tuber of Pueraria mirifica are given in Table 1, below.
TABLE 1 Contents of Isoflavones in Extract Derived from Tuber of Pueraria mirifica Isoflavone Content (mg/lOOg)
Daidzin 51.0
Daidzein 8.1
Genistin 12.0
Genistein 2.0
Puerarin 96.0
As shown in Table 1, the above processes can prepare the best quality of Pueraria mirifica powder. The powder prepared according to the above processes was measured to be high in its contents of isoflavone and other phytoestrogens. Phytoestrogens obtained from the plant included miroesterol, daidzin, genistin, genistein, beta-sitosterol, stigmasterol, coumestrol, puerarin, campesterol, mirificoumestan, kwakhurin, and mirificin (Bounds and Pope, 1960; Ingham et al., 1986a; Ingham et al, 1986b; Ingham et al., 1988).

But if you happen to make it please be careful, as the extract is extremely strong. At the place I found it they warned multiple times about the strength. If you make a cream or lotion with it, the maximum one should use is 4% of the topical you are trying to make. If anyone is interested in the exact recipe for lotions or creams, just say so and I will load them up as well.

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#10

try these website:

https://patents.google.com/patent/US6352685B2/en


https://patents.google.com/patent/US20040105900A1/en
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